phospho GluR2 (Tyr876) Antibody | EMD Millipore AB2297 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho GluR2 (Tyr876) Antibody

catalog :

AB2297

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 2e	Baglietto Vargas D, Prieto G, Limon A, Forner S, Rodriguez Ortiz C, Ikemura K, et al. Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease. Aging Cell. 2018;17:e12791 pubmed publisher

product information

Catalog Number :

AB2297

Subcategory :

Neuroscience

Product Name :

Anti-phospho GluR2 (Tyr876) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P19491

Host Name :

Rabbit

Antigen :

phospho GluR2 (Tyr876)

Conjugate :

Affinity Purified

Isotype :

IgG

Product Description :

Anti-phospho GluR2 (Tyr876) Antibody

Cross Reactivity :

Rat

Background :

Glutamate receptors (GluRs) can be categorized as ionotropic or metabotropic and subcatergorized by their agonist preferences (NMDA, AMPA or Kainic acid). There are four types of AMPA selective GluR subunits (GluR1, GluR2, GluR3 and GluR4). Tetrameric or pentameric combinations of different subunits contributes to the functional diversity of AMPA receptors. In general, AMPA receptors mediate fast synaptic current at most excitatory synapses, with stoichiometry characterized by subtype composition. Phosphorylation of tyrosine 876 (Tyr876) near the C terminus of GluR2 is thought to be instrumental in the control of AMPA receptor function and synaptic plasticity.

ALT Names :

Glutamate receptor 2;GluR-2;AMPA-selective glutamate receptor 2;GluR-B;GluR-K2;Glutamate receptor ionotropic, AMPA 2;GluA2

Immunogen :

Linear peptide corresponding to rat GluR2 phosphorylated at Tyr869, Tyr873, and Tyr876.

Specificity :

This antibody recognizes GluR2 phosphorylated at Tyr869, Tyr873, and Tyr876.

Package Size :

100 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt