MAP2, Alexa Fluor® 488 Conjugate Antibody | EMD Millipore AB2290A4 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MAP2, Alexa Fluor® 488 Conjugate Antibody

catalog :

AB2290A4

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

AF488

reactivity :

rat

application :

immunohistochemistry, immunocytochemistry

product information

Catalog Number :

AB2290A4

Subcategory :

Neuroscience

Product Name :

Anti-MAP2, Alexa Fluor® 488 Conjugate Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P15146

Host Name :

Rabbit

Antigen :

MAP2

Conjugate :

AlexaFluor®488

Product Description :

Anti-MAP2, Alexa Fluor® 488 Conjugate Antibody

Cross Reactivity :

Rat

Background :

The microtubule-associated protein 2 (MAP-2) is an abundant neuronal cytoskeletal protein that binds to tubulin, stabilizes microtubules (Herzog and Weber, 1978), and is an excellent marker for neurons. MAP-2 is essential for the development and maintenance of neuronal morphology (Matus, 1991). Three primary isoforms of MAP-2, the high molecular weight MAP2a and MAP2b, and the low molecular weight MAP2c (resulting from alternate splicing of the MAP2 gene), have been identified in neurours. (Chung et al., 1996). The low molecular weight isoform, MAP2c, is expressed in developing brain and is down-regulated during brain maturation, whereas the high molecular weight MAP2b is expressed in both developing and adult brain. The MAP2a appears only after brain maturation (Tucker, 1990). All these forms bind to microtubules through a domain near the carboxyl terminus that contains either three or four similar repeats of a 31-amino-acid motif (Lewis et al., 1988). MAP-2 together with MAP-4 and tau proteins belong to the family of thermostable proteins associated with microtubules.

ALT Names :

Microtubule-associated protein 2;MAP-2;MAP2

Immunogen :

Three KLH-conjugated linear peptides corresponding to the N-terminal and central regions of rat MAP-2.

Package Size :

100 µL

Uses :

Immunocytochemistry;Immunohistochemistry

Storage :

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.