MAP-2 Antibody | EMD Millipore AB2290 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MAP-2 Antibody

catalog :

AB2290

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Tian J, Chen W, Cui J, Wang H, Chao C, Lu Z, et al. Effect of Lycium bararum polysaccharides on methylmercury-induced abnormal differentiation of hippocampal stem cells. Exp Ther Med. 2016;12:683-689 pubmed

product information

Catalog Number :

AB2290

Subcategory :

Neuroscience

Product Name :

Anti-MAP-2 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P15146

Host Name :

Rabbit

Antigen :

MAP-2

Conjugate :

Affinity Purified

Product Description :

Anti-MAP-2 Antibody

Cross Reactivity :

Rat

Background :

The microtubule-associated protein 2 (MAP-2) is an abundant neuronal cytoskeletal protein that binds to tubulin and stabilizes microtubules. (Herzog and Weber, 1978). MAP-2 is essential for the development and maitenance of neuronal morphology (Matus, 1991). Three primary isoforms of MAP-2, the high molecular weight MAP2a and MAP2b, and the low molecular weight MAP2c (resulting from alternate splicing of the MAP2 gene), have been identified in neurons. (Chung et al., 1996). The low molecular weight isoform, MAP2c, is expressed in developing brain and is down-regulated during brain maturation, whereas the high molecular weight MAP2b is expressed in both developing and adult brain. The MAP2a appears only after brain maturation (Tucker, 1990). All these forms bind to microtubules through a domain near the carboxyl terminus that contains either three or four similar repeats of a 31-amino-acid motif (Lewis et al., 1988). MAP-2 together with MAP-4 and tau proteins belong to the family of thermostable proteins associated with microtubules.

ALT Names :

microtubule-associated protein 2;MAP2;MAP 2

Immunogen :

Three KLH-conjugated linear peptides corresponding to the N-terminal and central regions of rat MAP-2 .

Specificity :

This antibody recognizes MAP-2.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt