RBP-jk Antibody | EMD Millipore AB2284 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

RBP-jk Antibody

catalog :

AB2284

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, chicken, zebrafish

application :

western blot

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 4o	Nakagawa N, Li J, Yabuno Nakagawa K, Eom T, Cowles M, Mapp T, et al. APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017;31:1679-1692 pubmed publisher
	Kohnken R, Wen J, Mundy Bosse B, McConnell K, Keiter A, Grinshpun L, et al. Diminished microRNA-29b level is associated with BRD4-mediated activation of oncogenes in cutaneous T-cell lymphoma. Blood. 2017;: pubmed publisher

product information

Catalog Number :

AB2284

Subcategory :

Neuroscience

Product Name :

Anti-RBP-jk Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q06330

Host Name :

Rabbit

Antigen :

RBP-jk

Conjugate :

Purified

Product Description :

Anti-RBP-jk Antibody

Cross Reactivity :

Rat;Mouse;Human;Chicken;Drosophila;Horse;Nematode;Zebrafish

Background :

RBP-jk, Recombinant signal binding protein for immunoglobin kappa J region, is a human homolog for the Drosophila gene, suppressor of hairless. RBP-jk is located in the nucleus and is a 60 kDa monomeric protein that is used as a promoter region in notch signaling. Notch signaling is important in cell to cell communication which allows "a differentiating cell to suppress the same differentiation fate in a neighboring cell (the receiving cell). This ensures that the correct number of cells are distributed to distinct cell fates." When RBP-jk is not associated with Notch proteins, it acts as a transcriptional repressor. A disease associated with RBP-jk is the Epstein Barr virus.

ALT Names :

H-2K binding factor-2;J kappa-recombination signal-binding protein;RBP-J kappa ;Renal carcinoma antigen NY-REN-30 ;immunoglobulin kappa J region recombination signal binding protein 1 ;recombination signal binding protein for immunoglobulin kappa J region;recombining binding protein suppressor of hairless ;recombining binding protein suppressor of hairless (Drosophila) ;suppressor of hairless homolog

Immunogen :

Synthetic Linear peptide corresponding to the Beta-Trefoil Domain a.a. 194-206 of RBP-jk conjugated to KLH.

Specificity :

Cat. # AB2284 recognizes the Beta-Trefoil Domain of RBP-jk.

Package Size :

100 µg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8ºC from date of receipt.