Tid1 Antibody | EMD Millipore AB2271 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Tid1 Antibody

catalog :

AB2271

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dog, cow, chimpanzee

application :

western blot, immunohistochemistry

product information

Catalog Number :

AB2271

Subcategory :

Neuroscience

Product Name :

Anti-Tid1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q96EY1

Host Name :

Rabbit

Antigen :

Tid1

Conjugate :

Affinity Purified

Product Description :

Anti-Tid1 Antibody

Cross Reactivity :

Human;Mouse;Rat;Bovine;Chimpanzee;Canine;Rhesus Macaque

Background :

Tumorous imaginal disc 1 (Tid1) is a regulatory protein, comprised of a CR-type zinc finger and a J domain, belonging to DnaJ family of cochaperones/specificity factors for the Hsp70 family. Tid1 is involved in regulating several cellular processes such as cell proliferation, induction of apoptosis, and cell survival. Although mainly localized to mitochondria, most of the functions performed by Tid1 are nonmitochondrial. Tid1 induces the release of mitochondrial cytochrome C and activates caspase 3. In humans, Tid1 expression produces two splice variant isoforms that each serve a contrasting role in apoptotic regulation; Tid1-L (43 kDa) upregulates apoptosis in response to either mytomyocin C or TNF, and Tid1-S (40 kDa) serves to suppress apoptotic activity. The highest levels of expression have been observed in the liver, lung, heart and skeletal muscle, as well as in keratinocytes. Originally, it was described as interacting with the HPV E7 oncoprotein.

ALT Names :

DnaJ (Hsp40) homolog, subfamily A, member 3;DnaJ protein Tid-1;Tumorous imaginal discs protein Tid56 homolog;Hepatocellular carcinoma-associated antigen 57;dnaJ homolog subfamily A member 3, mitochondrial;tumorous imaginal discs homolog

Immunogen :

KLH-conjugated linear peptide corresponding to human Tid1 at the J domain.

Specificity :

This antibody recognizes Tid1 at the J domain.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt