Tbr1 Antibody | EMD Millipore AB2261 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Tbr1 Antibody

catalog :

AB2261

quantity :

100 μg

clonality :

polyclonal

host :

chicken

conjugate :

nonconjugated

reactivity :

human, mouse, dogs, chicken, bovine

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:500; loading ...; fig s1c	Rashid M, Belmont J, Carpenter D, Turner C, Olson E. Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation. Development. 2017;144:4002-4014 pubmed publisher
immunohistochemistry; mouse; 1:2500; loading ...; fig 2u	Nakagawa N, Li J, Yabuno Nakagawa K, Eom T, Cowles M, Mapp T, et al. APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017;31:1679-1692 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig 4-s2	Dragich J, Kuwajima T, Hirose Ikeda M, Yoon M, Eenjes E, Bosco J, et al. Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain. elife. 2016;5: pubmed publisher
immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 1c	Wang L, Hou S, Han Y. Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. Nat Neurosci. 2016;19:888-96 pubmed publisher
immunohistochemistry - frozen section; chicken; 1:500; fig s1	Nomura T, Ohtaka Maruyama C, Yamashita W, Wakamatsu Y, Murakami Y, Calegari F, et al. The evolution of basal progenitors in the developing non-mammalian brain. Development. 2016;143:66-74 pubmed publisher
	Oboti L, Russo E, Tran T, Durstewitz D, Corbin J. Amygdala Corticofugal Input Shapes Mitral Cell Responses in the Accessory Olfactory Bulb. Eneuro. 2018;5: pubmed publisher
	LaConte L, Chavan V, Elias A, Hudson C, Schwanke C, Styren K, et al. Two microcephaly-associated novel missense mutations in CASK specifically disrupt the CASK-neurexin interaction. Hum Genet. 2018;137:231-246 pubmed publisher
	McClendon E, Shaver D, Degener O Brien K, Gong X, Nguyen T, Hoerder Suabedissen A, et al. Transient Hypoxemia Chronically Disrupts Maturation of Preterm Fetal Ovine Subplate Neuron Arborization and Activity. J Neurosci. 2017;37:11912-11929 pubmed publisher

product information

Catalog Number :

AB2261

Subcategory :

Neuroscience

Product Name :

Anti-Tbr1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q64336

Host Name :

Chicken

Antigen :

Tbr1

Conjugate :

Affinity Purified

Product Description :

Anti-Tbr1 Antibody

Cross Reactivity :

Human;Mouse;Rat;Horse;Pig;Opossum;Bovine;Canine

Background :

Tbr1 gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Tbr1, a putative transcription factor known to be expressed in post-mitotic neurons, has been found highly expressed in glutamatergic early-born cortical neurons. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region the Tbr1 derived protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.

ALT Names :

T-box, brain, 1

Immunogen :

KLH-conjugated linear peptide corresponding to mouse Tbr1.

Specificity :

This antibody recognizes Tbr1.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt