GABA B Receptor R1 Antibody | EMD Millipore AB2256 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

GABA B Receptor R1 Antibody

catalog :

AB2256

quantity :

50 µL

clonality :

polyclonal

host :

guinea-pigs

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

citations: 3

Reference
Nagai J, Rajbhandari A, Gangwani M, Hachisuka A, Coppola G, Masmanidis S, et al. Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue. Cell. 2019;177:1280-1292.e20 pubmed publisher
Kang J, Chadchankar J, Vien T, Mighdoll M, Hyde T, Mather R, et al. Deficits in the activity of presynaptic γ-aminobutyric acid type B receptors contribute to altered neuronal excitability in fragile X syndrome. J Biol Chem. 2017;292:6621-6632 pubmed publisher
Mazo C, Lepousez G, Nissant A, Valley M, Lledo P. GABAB Receptors Tune Cortical Feedback to the Olfactory Bulb. J Neurosci. 2016;36:8289-304 pubmed publisher

product information

Catalog Number :

AB2256

Subcategory :

Neuroscience

Product Name :

Anti-GABA B Receptor R1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q9Z0U4

Host Name :

Guinea Pig

Antigen :

GABA B Receptor R1

Conjugate :

Serum

Product Description :

Anti-GABA B Receptor R1 Antibody

Cross Reactivity :

Rat;Mouse;Human

Background :

Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants.

ALT Names :

GABA-B receptor ;GABA-B receptor 1;GABAB, subunit 1c ;gamma-aminobutyric acid (GABA) B receptor 1;gamma-aminobutyric acid B receptor, 1 ;seven transmembrane helix receptor

Immunogen :

Recombinant peptide (aa 972-991: PSEPPDRLSCDGSRVHLLYK)

Specificity :

Cat. # AB2256 recognizes GABA B Receptor R1 (GABA B R1)

Package Size :

50 µL

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at -20ºC from date of receipt.