MDGA1 Antibody | EMD Millipore AB2226 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MDGA1 Antibody

catalog :

AB2226

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, cow

application :

western blot

product information

Catalog Number :

AB2226

Subcategory :

Neuroscience

Product Name :

Anti-MDGA1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q8NFP4

Host Name :

Rabbit

Antigen :

MDGA1

Conjugate :

Affinity Purified

Product Description :

Anti-MDGA1 Antibody

Cross Reactivity :

Mouse;Rat;Bovine;Human

Background :

Studies report that MDGA1 is a layer-specific marker and an area-specific marker, being expressed in layers 2/3 throughout the neocortex, but within the primary somatosensory area (S1), MDGA1 is also uniquely expressed in layers 4 and 6a. Comparisons with other markers, including cadherins, serotonin, cytochrome oxidase, RORß, and COUP-TF1, reveal unique features of patterned expression of MDGA1 within cortex and S1 barrels. Furthermore, during early stages of development, MDGA1 is expressed by Reelin- and Tbr1-positive Cajal–Retzius neurons that originate from multiple sources outside of neocortex and emigrate into it. At even earlier stages, MDGA1 is expressed by the earliest diencephalic and mesencephalic neurons, which appear to migrate from a MDGA1-positive domain of progenitors in the diencephalon and form a "preplate." These findings show that MDGA1 is a unique marker for studies of cortical lamination and area patterning and together with recent reports suggest that MDGA1 has critical functions in forebrain/midbrain development.

ALT Names :

MAM domain-containing glycosylphosphatidylinositol anchor protein 1;GPI and MAM protein;GPIM;Glycosylphosphatidylinositol-MAM;MAM domain-containing protein 3

Immunogen :

KLH-conjugated linear peptide corresponding to the MAM domain of MDGA1.

Specificity :

This antibody recognizes the MAM domain of MDGA1.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt