Fibronectin Antibody | EMD Millipore AB2033 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Fibronectin Antibody

catalog :

AB2033

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, radioimmunoassay, immunohistochemistry - paraffin section

citations: 15

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:5000; loading ...; fig 7a	Bozic M, Caus M, Rodrigues Díez R, Pedraza N, Ruiz Ortega M, Garí E, et al. Protective role of renal proximal tubular alpha-synuclein in the pathogenesis of kidney fibrosis. Nat Commun. 2020;11:1943 pubmed publisher
immunocytochemistry; rat; 1:100; loading ...; fig 2a, 2b	Werkman I, Sikkema A, Versluijs J, Qin J, de Boer P, Baron W. TLR3 agonists induce fibronectin aggregation by activated astrocytes: a role of pro-inflammatory cytokines and fibronectin splice variants. Sci Rep. 2020;10:532 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 7d western blot; human; 1:1000; loading ...; fig 4d	Rubio K, Singh I, Dobersch S, Sarvari P, Günther S, Cordero J, et al. Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis. Nat Commun. 2019;10:2229 pubmed publisher
immunocytochemistry; human; 1:500; loading ...; fig 8a	Hubmacher D, Schneider M, Berardinelli S, Takeuchi H, Willard B, Reinhardt D, et al. Unusual life cycle and impact on microfibril assembly of ADAMTS17, a secreted metalloprotease mutated in genetic eye disease. Sci Rep. 2017;7:41871 pubmed publisher
immunocytochemistry; mouse; 1:300-1:500; loading ...; fig 4b immunohistochemistry; mouse; 1:300-1:500; loading ...; fig 1b western blot; mouse; 1:2000; loading ...; fig 1-s2	Benito JardÃ³n M, Klapproth S, Gimeno LLuch I, Petzold T, Bharadwaj M, MÃ¼ller D, et al. The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes. elife. 2017;6: pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:500; fig s4	Dubail J, Vasudevan D, Wang L, Earp S, Jenkins M, Haltiwanger R, et al. Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome. Sci Rep. 2016;6:33974 pubmed publisher
western blot; mouse; 1:1000; tbl 2	Muñoz Félix J, Pérez Roque L, Núñez Gómez E, Oujo B, Arevalo M, Ruiz Remolina L, et al. Overexpression of the short endoglin isoform reduces renal fibrosis and inflammation after unilateral ureteral obstruction. Biochim Biophys Acta. 2016;1862:1801-14 pubmed publisher
western blot; mouse; 1:5000; fig 7	Rubio Navarro A, Carril M, Padro D, Guerrero Hue M, Tarin C, Samaniego R, et al. CD163-Macrophages Are Involved in Rhabdomyolysis-Induced Kidney Injury and May Be Detected by MRI with Targeted Gold-Coated Iron Oxide Nanoparticles. Theranostics. 2016;6:896-914 pubmed publisher
immunocytochemistry; mouse; 1:500; fig 2	Theodosiou M, Widmaier M, BÃ¶ttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:1000; fig 4	Allaire J, Roy S, Ouellet C, Lemieux Ã, Jones C, Paquet M, et al. Bmp signaling in colonic mesenchyme regulates stromal microenvironment and protects from polyposis initiation. Int J Cancer. 2016;138:2700-12 pubmed publisher
	Williams H, Ma J, Weiss D, LASSEGUE B, Sutliff R, San Martin A. The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo. Lab Invest. 2019;99:399-410 pubmed publisher
	Kumra H, Sabatier L, Hassan A, Sakai T, Mosher D, Brinckmann J, et al. Roles of fibronectin isoforms in neonatal vascular development and matrix integrity. PLoS Biol. 2018;16:e2004812 pubmed publisher
	Yoshida S, Yamahara K, Kume S, Koya D, Yasuda Yamahara M, Takeda N, et al. Role of dietary amino acid balance in diet restriction-mediated lifespan extension, renoprotection, and muscle weakness in aged mice. Aging Cell. 2018;17:e12796 pubmed publisher
	Lenoir O, Jasiek M, Henique C, Guyonnet L, Hartleben B, Bork T, et al. Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis. Autophagy. 2015;11:1130-45 pubmed publisher
	Sekine K, Kawauchi T, Kubo K, Honda T, Herz J, Hattori M, et al. Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin ?5?1. Neuron. 2012;76:353-69 pubmed publisher

product information

Catalog Number :

AB2033

Subcategory :

Cell Structure

Product Name :

Anti-Fibronectin Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P02751

Host Name :

Rabbit

Antigen :

Fibronectin

Conjugate :

Affinity Purified

Product Description :

Anti-Fibronectin Antibody

Cross Reactivity :

Mouse

Background :

Fibronectin is a high molecular weight extracellular adhesion molecule involved in many cellular processes, including tissue repair or wound healing, embryogenesis, blood clotting, and cell migration/adhesion. Fibronectin exists in two major forms: 1) as an insoluble glycoprotein dimer that serves as a linker in the extracellular matrix (ECM), and 2) as a soluble disulfide-linked dimer found in the plasma. The plasma form is synthesized by hepatocytes, and the ECM form is made by fibroblasts, chondrocytes, endothelial cells, macrophages, as well as certain epithelial cells. Fibronectin sometimes serves as a general cell adhesion molecule by anchoring cells to collagen or proteoglycan substrates. It can also serve to organize cellular interaction with the ECM by binding to different components of the ECM and to membrane-bound fibronectin receptors on cell surfaces. The immunogen for fibronectin polyclonal antibody AB2033 is purified mouse plasma. The antibody shows less than 0.1% reactivity with mouse laminin, and collagen types I, III, and IV by radioimmunoassay.

Immunogen :

Fibronectin extracted and purified from mouse plasma.

Specificity :

This antibody reacts with mouse fibronectin. Shows less than 0.1% reactivity with mouse Laminin, and Collagen Types I, III, and IV by radioimmunoassay.

Package Size :

100 μg

Uses :

ELISA;Immunocytochemistry;Immunohistochemistry;Radioimmunoassay

Storage :

Stable for 1 year at -20ºC from date of receipt.