Integrin beta1, phospho-specific [Ser785] | EMD Millipore AB1927 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Integrin beta1, phospho-specific [Ser785]

catalog :

AB1927

quantity :

100 uL

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, chicken

application :

western blot

citations: 1

Reference
Davis J, Metzger J. Combinatorial effects of double cardiomyopathy mutant alleles in rodent myocytes: a predictive cellular model of myofilament dysregulation in disease. PLoS ONE. 2010;5:e9140 pubmed publisher

product information

Catalog Number :

AB1927

Category :

Antibodies

Subcategory :

Cell Structure

Product Name :

Anti-Integrin beta1, phospho-specific [Ser785]

Product Type :

Antibodies

Clonality :

Polyclonal

Gene ID :

NM_002211.2, NM_033666.1, NM_033667.1, NM_033668.1, NM_033669.1, NM_133376.1

Host Name :

Conjugate :

Affinity Purified

Product Description :

Anti-Integrin beta1, phospho-specific [Ser785]

Cross Reactivity :

Mouse, Chicken

Background :

Integrin beta1 is a transmembrane glycoprotein that forms noncovalent complexes with various alpha integrin subunits to form the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumor cells. Interactions between integrins and extracellular matrix lead to activation of signal transduction pathways and regulation of gene expression. Phosphorylation of serine 785 on integrin beta1 promotes cell attachment, but inhibits spreading and migration. In contrast, dephosphorylation promotes cell spreading and migration.

Immunogen :

Phosphorylated integrin beta1 (Ser785) synthetic peptide corresponding to human amino acid residues around serine 785. The sequence is conserved in mouse, rat and chicken.

Specificity :

The antibody detects a 130 kDa protein of integrin beta1.

Purity :

Immunoaffinity purified

Package Size :

100 uL

Uses :

Storage :

Maintain at -20°C for up to one year from date of receipt. Avoid repeated freeze/thaw cycles.