Caspase 3 Antibody, large subunit & proform | EMD Millipore AB1899 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Caspase 3 Antibody, large subunit & proform

catalog :

AB1899

quantity :

50 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

Catalog Number :

AB1899

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-Caspase 3 Antibody, large subunit & proform

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P42574

Host Name :

Rabbit

Antigen :

Caspase 3

Conjugate :

Affinity Purified

Product Description :

Anti-Caspase 3 Antibody, large subunit & proform

Cross Reactivity :

Human;Mouse;Rat

Background :

Caspase-3 (CPP32, Apopain) is the most extensively studied apoptotic protein. Caspase-3 is synthesized as an inactive proenzyme (32 kDa) that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-3 consists of large (17 kDa) and small (12 kDa) subunits which associate to form an active enzyme. The active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells such as PARP and DFF.

ALT Names :

apopain;procaspase3

Immunogen :

Synthetic peptide

Specificity :

AB1899 detects procaspase-3 (32 kDa) and the cleaved p20 fragment in cells undergoing apoptosis.

Package Size :

50 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.