Calbindin D-28K Antibody | EMD Millipore AB1778 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Calbindin D-28K Antibody

catalog :

AB1778

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section

citations: 27

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2a	Schoof M, Launspach M, Holdhof D, Nguyen L, Engel V, Filser S, et al. The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration. Acta Neuropathol Commun. 2019;7:199 pubmed publisher
immunohistochemistry; mouse; 1:200; loading ...; fig 5a	Saifetiarova J, Bhat M. Ablation of cytoskeletal scaffolding proteins, Band 4.1B and Whirlin, leads to cerebellar purkinje axon pathology and motor dysfunction. J Neurosci Res. 2019;97:313-331 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 2a	Chen X, Chanda A, Ikeuchi Y, Zhang X, Goodman J, Reddy N, et al. The Transcriptional Regulator SnoN Promotes the Proliferation of Cerebellar Granule Neuron Precursors in the Postnatal Mouse Brain. J Neurosci. 2019;39:44-62 pubmed publisher
immunohistochemistry; mouse; 1:250; loading ...; fig 4g	Gstrein T, Edwards A, Přistoupilová A, Leca I, Breuss M, Pilat Carotta S, et al. Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans. Nat Neurosci. 2018;21:207-217 pubmed publisher
immunohistochemistry; mouse; 1:200; loading ...; fig 1b	Turecek J, Jackman S, Regehr W. Synaptotagmin 7 confers frequency invariance onto specialized depressing synapses. Nature. 2017;551:503-506 pubmed publisher
immunohistochemistry; mouse; 1:1000; loading ...; fig s8j	Paul A, Chaker Z, Doetsch F. Hypothalamic regulation of regionally distinct adult neural stem cells and neurogenesis. Science. 2017;356:1383-1386 pubmed publisher
immunohistochemistry; mouse; 1:200; fig 3B	Bucks S, Cox B, Vlosich B, Manning J, Nguyen T, Stone J. Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice. elife. 2017;6: pubmed publisher
immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 1f	Ha S, Tripathi P, Mihalas A, Hevner R, Beier D. C-Terminal Region Truncation of RELN Disrupts an Interaction with VLDLR, Causing Abnormal Development of the Cerebral Cortex and Hippocampus. J Neurosci. 2017;37:960-971 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 8d	Sambri I, D Alessio R, Ezhova Y, Giuliano T, Sorrentino N, Cacace V, et al. Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases. EMBO Mol Med. 2017;9:112-132 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:50; fig 6	Boggild S, Molgaard S, Glerup S, Nyengaard J. Spatiotemporal patterns of sortilin and SorCS2 localization during organ development. BMC Cell Biol. 2016;17:8 pubmed publisher
immunohistochemistry; mouse; 1:750; loading ...; fig 9b	Boye S, Bennett A, Scalabrino M, McCullough K, Van Vliet K, Choudhury S, et al. Impact of Heparan Sulfate Binding on Transduction of Retina by Recombinant Adeno-Associated Virus Vectors. J Virol. 2016;90:4215-4231 pubmed publisher
immunohistochemistry - free floating section; mouse; 1:500; fig 6	Jara J, Stanford M, Zhu Y, Tu M, Hauswirth W, Bohn M, et al. Healthy and diseased corticospinal motor neurons are selectively transduced upon direct AAV2-2 injection into the motor cortex. Gene Ther. 2016;23:272-82 pubmed publisher
immunohistochemistry; mouse; 1:1000; loading ...; fig 3e	Grishchuk Y, Stember K, Matsunaga A, Olivares A, CRUZ N, King V, et al. Retinal Dystrophy and Optic Nerve Pathology inÂ the Mouse Model of Mucolipidosis IV. Am J Pathol. 2016;186:199-209 pubmed publisher
immunohistochemistry; human; 1:500; loading ...; fig 4c	Uchida H, Morita T, Niizuma K, Kushida Y, Kuroda Y, Wakao S, et al. Transplantation of Unique Subpopulation of Fibroblasts, Muse Cells, Ameliorates Experimental Stroke Possibly via Robust Neuronal Differentiation. Stem Cells. 2016;34:160-73 pubmed publisher
	Wagner W, Lippmann K, Heisler F, Gromova K, Lombino F, Roesler M, et al. Myosin VI Drives Clathrin-Mediated AMPA Receptor Endocytosis to Facilitate Cerebellar Long-Term Depression. Cell Rep. 2019;28:11-20.e9 pubmed publisher
	Bruce K, Gorkhali S, Given K, Coates A, Boyle K, Macklin W, et al. Lipoprotein Lipase Is a Feature of Alternatively-Activated Microglia and May Facilitate Lipid Uptake in the CNS During Demyelination. Front Mol Neurosci. 2018;11:57 pubmed publisher
	Ogawa Y, Kakumoto K, Yoshida T, Kuwako K, Miyazaki T, Yamaguchi J, et al. Elavl3 is essential for the maintenance of Purkinje neuron axons. Sci Rep. 2018;8:2722 pubmed publisher
	Berg E, Bertuzzi M, Ampatzis K. Complementary expression of calcium binding proteins delineates the functional organization of the locomotor network. Brain Struct Funct. 2018;223:2181-2196 pubmed publisher
	Goodson N, Nahreini J, Randazzo G, Uruena A, Johnson J, Brzezinski J. Prdm13 is required for Ebf3+ amacrine cell formation in the retina. Dev Biol. 2018;434:149-163 pubmed publisher
	Travis A, Heflin S, Hirano A, Brecha N, Arshavsky V. Dopamine-Dependent Sensitization of Rod Bipolar Cells by GABA Is Conveyed through Wide-Field Amacrine Cells. J Neurosci. 2018;38:723-732 pubmed publisher
	Lin Y, Chen C, Huang C, Nishimori K, Hsu K. Oxytocin stimulates hippocampal neurogenesis via oxytocin receptor expressed in CA3 pyramidal neurons. Nat Commun. 2017;8:537 pubmed publisher
	Ornaghi S, Hsieh L, Bordey A, Vergani P, Paidas M, van den Pol A. Valnoctamide Inhibits Cytomegalovirus Infection in Developing Brain and Attenuates Neurobehavioral Dysfunctions and Brain Abnormalities. J Neurosci. 2017;37:6877-6893 pubmed publisher
	Clark R, Blizzard C, Young K, King A, Dickson T. Calretinin and Neuropeptide Y interneurons are differentially altered in the motor cortex of the SOD1G93A mouse model of ALS. Sci Rep. 2017;7:44461 pubmed publisher
	Shin Y, Moiseyev G, Chakraborty D, Ma J. A Dominant Mutation in Rpe65, D477G, Delays Dark Adaptation and Disturbs the Visual Cycle in the Mutant Knock-In Mice. Am J Pathol. 2017;187:517-527 pubmed publisher
	Fujiwara N, Cave J. Partial Conservation between Mice and Humans in Olfactory Bulb Interneuron Transcription Factor Codes. Front Neurosci. 2016;10:337 pubmed publisher
	Blosa M, Bursch C, Weigel S, Holzer M, JÃ¤ger C, Janke C, et al. Reorganization of Synaptic Connections and Perineuronal Nets in the Deep Cerebellar Nuclei of Purkinje Cell Degeneration Mutant Mice. Neural Plast. 2016;2016:2828536 pubmed publisher
	Sikora J, Leddy J, Gulinello M, Walkley S. X-linked Christianson syndrome: heterozygous female Slc9a6 knockout mice develop mosaic neuropathological changes and related behavioral abnormalities. Dis Model Mech. 2016;9:13-23 pubmed publisher

product information

Catalog Number :

AB1778

Subcategory :

Neuroscience

Product Name :

Anti-Calbindin D-28K Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P05937

Host Name :

Rabbit

Antigen :

Calbindin D-28K

Conjugate :

Affinity Purified

Product Description :

Anti-Calbindin D-28K Antibody

Cross Reactivity :

Human;Mouse;Rat

Background :

Calbindin D-28k is a member of a large family of intracellular calcium-binding proteins of the EF-hand related to calmodulin and troponin-C. The biological roles of Calbindin D-28k include, calcium regulation (including calcium transport and uptake, calcification of bone and teeth) and calcium related signalling in neurons and transiently in embryological development. This calbindin also has a role in protecting neurons from apoptotic cell death. Disregulation of this calbindin protein relates to several disease states. Decline in calbindin D-28k in hippocampal dentate granule cells correlates with the kindling model for epilepsy. Calbindin D-28k immunoreactivity is specifically absent from neuronal poplulations lost early in ALS, while substantial loss of neurons which do contain the protein occur in patients with Huntington's disease.

ALT Names :

Calbindin D28;RTVL-H protein;Vitamin D-dependent calcium-binding protein, avian-type 3;calbindin;calbindin 1, (28kD);calbindin 1, 28kDa

Immunogen :

Recombinant mouse calbindin.

Specificity :

Calbindin. Shows no cross-reactivity to calretinin by Western blot. The antibody produces specific staining of cerebellum Purkinje cells, molecular layer dendrites and axonal fibers, stains cell bodies and fibers in neuronal subpopulations.

Package Size :

100 µL

Uses :

Immunocytochemistry;Immunohistochemistry;Immunohistochemistry (Paraffin);Western Blotting

Storage :

Stable for 1 year at -20ºC in undiluted aliquots from date of receipt. Avoid repeated freeze/thaw cycles. During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 uL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.