GluR2 Antibody | EMD Millipore AB1768-I product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

GluR2 Antibody

catalog :

AB1768-I

quantity :

25 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s3b	Evonuk K, Doyle R, Moseley C, Thornell I, Adler K, Bingaman A, et al. Reduction of AMPA receptor activity on mature oligodendrocytes attenuates loss of myelinated axons in autoimmune neuroinflammation. Sci Adv. 2020;6:eaax5936 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 4g	Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, et al. Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model. Nat Commun. 2019;10:1365 pubmed publisher
	Wang S, Ko S, Jo S, Jo H, Han J, Kim Y, et al. Downregulation of SIRT2 by Chronic Stress Reduces Expression of Synaptic Plasticity-related Genes through the Upregulation of Ehmt2. Exp Neurobiol. 2019;28:537-546 pubmed publisher
	Blanco Suarez E, Liu T, Kopelevich A, Allen N. Astrocyte-Secreted Chordin-like 1 Drives Synapse Maturation and Limits Plasticity by Increasing Synaptic GluA2 AMPA Receptors. Neuron. 2018;100:1116-1132.e13 pubmed publisher
	Wang S, Ko S, Kim Y, Jo S, Lee S, Jung S, et al. Capsaicin upregulates HDAC2 via TRPV1 and impairs neuronal maturation in mice. Exp Mol Med. 2018;50:e455 pubmed publisher
	Derman R, Ferrario C. Enhanced incentive motivation in obesity-prone rats is mediated by NAc core CP-AMPARs. Neuropharmacology. 2018;131:326-336 pubmed publisher

product information

Catalog Number :

AB1768-I

Subcategory :

Neuroscience

Product Name :

Anti-GluR2 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P19491

Host Name :

Rabbit

Antigen :

GluR2

Conjugate :

Affinity Purified

Product Description :

Anti-GluR2 Antibody

Cross Reactivity :

Mouse;Rat;Human

Background :

Glutamate receptors (GluRs) can be categorized as ionotropic or metabotropic and subcatergorized by their agonist preferences (NMDA, AMPA or Kainic acid). There are four types of AMPA selective GluR subunits (GluR1, GluR2, GluR3 and GluR4). Tetrameric or pentameric combinations of different subunits contributes to the functional diversity of AMPA receptors. In general, AMPA receptors mediate fast synaptic current at most excitatory synapses, with stoichiometry characterized by subtype composition. Although subunit composition of AMPA receptors varies, they must contain at least one edited GluR2 subunit to be calcium impermeable. Relative calcium permeability in AMPA receptor channels may be significant in pathological neurotoxic damage and long term changes in nervous system responses.

ALT Names :

Glutamate receptor 2;GluR-2;AMPA-selective glutamate receptor 2;GluR-B;GluR-K2;Glutamate receptor ionotropic;AMPA 2;GluA2

Immunogen :

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of rat GluR2.

Specificity :

This antibody recognizes the cytoplasmic domain of Glutamate Receptor 2.

Package Size :

25 μg

Uses :

Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt