GABA Antibody Cat. No. AB175 | EMD Millipore AB175 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

GABA Antibody Cat. No. AB175

catalog :

AB175

quantity :

50 μL

clonality :

polyclonal

host :

guinea-pigs

conjugate :

nonconjugated

application :

immunohistochemistry, enzyme immunoassay, immunohistochemistry - paraffin section, other

citations: 3

Reference
Eavri R, Shepherd J, Welsh C, Flanders G, Bear M, Nedivi E. Interneuron Simplification and Loss of Structural Plasticity As Markers of Aging-Related Functional Decline. J Neurosci. 2018;38:8421-8432 pubmed publisher
He H, Shen W, Zheng L, Guo X, Cline H. Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity. Nat Commun. 2018;9:2893 pubmed publisher
Micheva K, Wolman D, Mensh B, Pax E, Buchanan J, Smith S, et al. A large fraction of neocortical myelin ensheathes axons of local inhibitory neurons. elife. 2016;5: pubmed publisher

product information

Catalog Number :

AB175

Subcategory :

Neuroscience

Product Name :

Anti-GABA Antibody Cat. No. AB175

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Host Name :

Guinea Pig

Antigen :

GABA Cat. No. AB175

Conjugate :

Serum

Product Description :

Anti-GABA Antibody Cat. No. AB175

Cross Reactivity :

Rat;All

Background :

GABA (g-aminobutyric acid) is the major inhibitory neurotransmitter in the central nervous system that is involved in the pathogenesis of certain neurological and psychiatric disorders. GABA is produced from glutamic acid in a reaction catalyzed by glutamic acid decarboxylase. GABA interacts with the GABAA and GABAB receptors, which are widely distributed throughout the nervous system and in a variety of cell types. The immunolocalization, neuronal distribution, and vesicular compartmentalization of neurotransmitter molecules and their precursors are important for understanding the modulation, regulation, and function of neurotransmitters in the nervous system.

Immunogen :

BSA-conjugated GABA-Glutaraldehyde

Specificity :

Recognizes GABA. Staining was blocked by preabsorbing with 100 μM GABA conjugated to glutaraldehyde. 500 μM of similar conjugations of glutamic acid, glutamate and taurine failed to block staining.

Package Size :

50 μL

Uses :

Immunohistochemistry (Paraffin);Enzyme Immunoassay (ELISA)

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.