Bid Antibody | EMD Millipore AB1735 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Bid Antibody

catalog :

AB1735

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunoprecipitation

product information

Catalog Number :

AB1735

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-Bid Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P55957

Host Name :

Rabbit

Antigen :

Bid

Conjugate :

Serum

Product Description :

Anti-Bid Antibody

Cross Reactivity :

Human;Mouse;Rat;Rabbit

Background :

Bid, a BH3 domain-containing proapoptotic Bcl-2 family member, is known to interact with Bcl-2 and Bax. It has been reported that Bid induces cytochrome c release from mitochondria following cleavage by caspase-8 in response to apoptotic stimuli transmitted through cell surface death receptors. The cytochrome c releasing activity of Bid was antagonized by Bcl-2. Mutation in the SH3 domain can diminish the cytochrome c releasing activity. In animal model studies, Bid-deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas.

Immunogen :

Recombinant full length GST-tagged mouse Bid protein

Specificity :

AB1735 recognizes Bid from human, mouse, rat and rabbit.

Package Size :

100 µL

Uses :

Western Blotting;Immunoprecipitation;Immunohistochemistry

Storage :

Store at -20°C for up to 12 months.