Connexin 43 Antibody, CT, cytosolic | EMD Millipore AB1728 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Connexin 43 Antibody, CT, cytosolic

catalog :

AB1728

quantity :

50 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig s2b	Vasquez C, Mezzano V, Kessler N, Swardh F, Ernestad D, Mahoney V, et al. Connexin43 expression in bone marrow derived cells contributes to the electrophysiological properties of cardiac scar tissue. Sci Rep. 2020;10:2617 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig 4	Folmsbee S, Wilcox D, Tyberghein K, De Bleser P, Tourtellotte W, van Hengel J, et al. ?T-catenin in restricted brain cell types and its potential connection to autism. J Mol Psychiatry. 2016;4:2 pubmed publisher
western blot; rat; loading ...	Dubash A, Kam C, Aguado B, Patel D, Delmar M, Shea L, et al. Plakophilin-2 loss promotes TGF-β1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes. J Cell Biol. 2016;212:425-38 pubmed publisher
	Kam C, Dubash A, Magistrati E, Polo S, Satchell K, Sheikh F, et al. Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43. J Cell Biol. 2018;217:3219-3235 pubmed publisher
	Nadeem L, Shynlova O, Mesiano S, Lye S. Progesterone Via its Type-A Receptor Promotes Myometrial Gap Junction Coupling. Sci Rep. 2017;7:13357 pubmed publisher
	Yang L, Geng Z, Nickel T, Johnson C, Gao L, Dutton J, et al. Differentiation of Human Induced-Pluripotent Stem Cells into Smooth-Muscle Cells: Two Novel Protocols. PLoS ONE. 2016;11:e0147155 pubmed publisher
	Lim K, Hexiu J, Kim J, Seonwoo H, Choung P, Chung J. Synergistic effects of orbital shear stress on in vitro growth and osteogenic differentiation of human alveolar bone-derived mesenchymal stem cells. Biomed Res Int. 2014;2014:316803 pubmed publisher

product information

Catalog Number :

AB1728

Subcategory :

Cell Structure

Product Name :

Anti-Connexin 43 Antibody, CT, cytosolic

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P17302

Host Name :

Rabbit

Antigen :

Connexin 43

Conjugate :

Affinity Purified

Product Description :

Anti-Connexin 43 Antibody, CT, cytosolic

Cross Reactivity :

Human;Mouse;Rat

Background :

Connexin 43 (GJA1) is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. GJA1 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. GJA1 is targeted by several protein kinases that regulate myocardial cell cell coupling. A related intronless GJA1 pseudogene, GJA1P, has been mapped to chromosome 5. Mouse Connexin 43 is a 382 amino acid gap junction protein with a predicted M.W. of ~43 kDa. It is prominently expressed in heart (Kumar, N. and Giula, N., 1996, Cell 84: 381-388).

ALT Names :

Gap Junction alpha-1 Protein (CxA-1)

Immunogen :

Anti-Connexin 43 is made against a 23 amino acid C-terminal peptide sequence within the cytoplasmic domain of mouse C×43 (Beyer, E. and Steinberg, T. ,1991, JBC 266: 7971).

Specificity :

Recognizes mouse Connexin 43.

Package Size :

50 µg

Uses :

ELISA;Immunofluorescence;Immunohistochemistry;Immunoprecipitation;Western Blotting

Storage :

Stable for up to 1 year at 2-8°C in undiluted aliquots from date of receipt.