Substance P Antibody, pain | EMD Millipore AB1566 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Substance P Antibody, pain

catalog :

AB1566

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunocytochemistry, radioimmunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; rat; 1:100; fig 4	Xu Y, Liu J, He M, Liu R, Belegu V, Dai P, et al. Mechanisms of PDGF siRNA-mediated inhibition of bone cancer pain in the spinal cord. Sci Rep. 2016;6:27512 pubmed publisher
immunocytochemistry; mouse; 1:500; tbl 1	Hirata H, Umemori J, Yoshioka H, Koide T, Watanabe K, Shimoda Y. Cell adhesion molecule contactin-associated protein 3 is expressed in the mouse basal ganglia during early postnatal stages. J Neurosci Res. 2016;94:74-89 pubmed publisher
	Salvatierra J, Diaz Bustamante M, Meixiong J, Tierney E, Dong X, Bosmans F. A disease mutation reveals a role for NaV1.9 in acute itch. J Clin Invest. 2018;128:5434-5447 pubmed publisher
	Bignami F, Giacomini C, Lorusso A, Aramini A, Rama P, Ferrari G. NK1 receptor antagonists as a new treatment for corneal neovascularization. Invest Ophthalmol Vis Sci. 2014;55:6783-94 pubmed publisher

product information

Catalog Number :

AB1566

Subcategory :

Neuroscience

Product Name :

Anti-Substance P Antibody, pain

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P20366

Host Name :

Rabbit

Antigen :

Substance P

Conjugate :

Serum

Product Description :

Anti-Substance P Antibody, pain

Cross Reactivity :

Human;Mouse;Rat

Background :

Substance P is a tachykinin family neuropeptide that functions as a neurotransmitter and neuromodulator. In the CNS, Substance P is involved in the regulation of mood, anxiety, sleep, saiety, reinforcement, respiratory rhythm and pain processing. In nociception, the neuropeptide is released at local spinal cord synapse. Recent research now shows substance P is potentially involved in endothelial cell differentiation as well as diverse roles in neuroinflammatory response. The endogenous receptor for Substance P is neurokinin 1 receptor (NK1 receptor), which belongs to the tachykinin receptor sub-family of GPCRs.

Immunogen :

Substance P

Specificity :

Substance P

Package Size :

100 µL

Uses :

Immunohistochemistry (Paraffin);Radioimmunoassay

Storage :

Stable for 1 year at -20ºC from date of receipt.