HuD Antibody | EMD Millipore AB15644 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

HuD Antibody

catalog :

AB15644

quantity :

100 µg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dog, cow

application :

western blot

product information

Catalog Number :

AB15644

Subcategory :

Neuroscience

Product Name :

Anti-HuD Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P26378

Host Name :

Rabbit

Antigen :

HuD

Conjugate :

Purified

Product Description :

Anti-HuD Antibody

Cross Reactivity :

Human;Rat;Mouse

Background :

ELAV-like protein 4 (ELAVL4) also know as Human neuron-specific RNA-binding protein HuD belongs to the family of Hu proteins and consists of two N-terminal RNA recognition motifs (RRM1 and -2), a hinge region, and a C-terminal RRM (RRM3). Characteristically, these homologs all contain three RNA recognition motifs (RRM), and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts. ARE sites target mRNA for rapid degradation and thereby regulate the expression levels of genes involved in cell growth and differentiation. HuD is localized and expressed in brain tissue immediately after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance. HuD has been linked with the disease, paraneoplastic encephalomyelitis sensory neuropathy, which is associated with small cell lung cancer and is characterized by dementia, sensory loss, and other neurological disabilities.

ALT Names :

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D);ELAV-like 4;Embryonic lethal, abnormal vision, Drosophila, homolog of, like-4 ;Hu-antigen D;Paraneoplastic encephalomyelitis antigen HuD

Immunogen :

KLH-conjugated linear peptide a.a. 26-42.

Specificity :

Antibody recognizes HuD.

Package Size :

100 µg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8ºC from date of receipt.