Nerve Growth Factor Receptor Antibody, p75 | EMD Millipore AB1554 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Nerve Growth Factor Receptor Antibody, p75

catalog :

AB1554

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, chicken

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 14

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 4a immunocytochemistry; human; 2 ug/ml; loading ...; fig 4b	Bandeira F, Goh T, Setiawan M, Yam G, Mehta J. Cellular therapy of corneal epithelial defect by adipose mesenchymal stem cell-derived epithelial progenitors. Stem Cell Res Ther. 2020;11:14 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:200; loading ...	Gerber D, Ghidinelli M, Tinelli E, Somandin C, Gerber J, Pereira J, et al. Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function. elife. 2019;8: pubmed publisher
immunocytochemistry; mouse; 1:500; loading ...; fig 1b western blot; mouse; 1:1000; loading ...; fig 1c	Rizzi C, Tiberi A, Giustizieri M, Marrone M, Gobbo F, Carucci N, et al. NGF steers microglia toward a neuroprotective phenotype. Glia. 2018;66:1395-1416 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200; fig 2q	Schulz A, Büttner R, Hagel C, Baader S, Kluwe L, Salamon J, et al. The importance of nerve microenvironment for schwannoma development. Acta Neuropathol. 2016;132:289-307 pubmed publisher
immunocytochemistry; human; 1:100; fig s1	Xue Y, Qian H, Hu J, Zhou B, Zhou Y, Hu X, et al. Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells. Nat Neurosci. 2016;19:807-15 pubmed publisher
immunocytochemistry; human; 1:100; fig s4	Deborde S, Omelchenko T, Lyubchik A, Zhou Y, He S, McNamara W, et al. Schwann cells induce cancer cell dispersion and invasion. J Clin Invest. 2016;126:1538-54 pubmed publisher
immunocytochemistry; human; 1:100; fig 2	Zhang J, Weng Z, Tsang K, Tsang L, Chan H, Jiang X. MycN Is Critical for the Maintenance of Human Embryonic Stem Cell-Derived Neural Crest Stem Cells. PLoS ONE. 2016;11:e0148062 pubmed publisher
immunohistochemistry; mouse; 1:1000; loading ...; tbl 2	Schill E, Lake J, Tusheva O, Nagy N, Bery S, Foster L, et al. Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse. Dev Biol. 2016;409:473-88 pubmed publisher
	Rosenberg L, Cattin A, Fontana X, Harford Wright E, Burden J, White I, et al. HDAC3 Regulates the Transition to the Homeostatic Myelinating Schwann Cell State. Cell Rep. 2018;25:2755-2765.e5 pubmed publisher
	Chartier S, Mitchell S, Majuta L, Mantyh P. The Changing Sensory and Sympathetic Innervation of the Young, Adult and Aging Mouse Femur. Neuroscience. 2018;387:178-190 pubmed publisher
	Kasemeier Kulesa J, Romine M, Morrison J, Bailey C, Welch D, Kulesa P. NGF reprograms metastatic melanoma to a bipotent glial-melanocyte neural crest-like precursor. Biol Open. 2018;7: pubmed publisher
	Clements M, Byrne E, Camarillo Guerrero L, Cattin A, Zakka L, Ashraf A, et al. The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration. Neuron. 2017;96:98-114.e7 pubmed publisher
	Bakst R, Xiong H, Chen C, Deborde S, Lyubchik A, Zhou Y, et al. Inflammatory Monocytes Promote Perineural Invasion via CCL2-Mediated Recruitment and Cathepsin B Expression. Cancer Res. 2017;77:6400-6414 pubmed publisher
	Ingram N, Khankan R, Phelps P. Olfactory Ensheathing Cells Express ?7 Integrin to Mediate Their Migration on Laminin. PLoS ONE. 2016;11:e0153394 pubmed publisher

product information

Catalog Number :

AB1554

Subcategory :

Neuroscience

Product Name :

Anti-Nerve Growth Factor Receptor Antibody, p75

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P08138

Host Name :

Rabbit

Antigen :

Nerve Growth Factor Receptor

Conjugate :

Serum

Product Description :

Anti-Nerve Growth Factor Receptor Antibody, p75

Cross Reactivity :

Chicken;Human;Mouse;Rat

Background :

Nerve Growth Factor Receptor, also termed NGFR p75, p75NTR, or CD271 is the low affinity NGFR (LNGFR) which binds NGF and other neurotrophins including BDNF, NT3, NT4/5 with similar, low affinity. NGFR p75 is a 75 kDa transmembrane glycoprotein (399 a.a.) consisting of an extracellular domain (222 a.a.) which contains four cysteine rich domains responsible for ligand binding, a transmembrane domain (22 a.a.), and a cytoplasmic domain (155 a.a.). NGFR p75 is mainly expressed in Schwann cells and neurons and in a variety of non neuronal cells. NGFR p75 is necessary for regulating neuronal growth, migration, differentiation and cell death during development of the central and peripheral nervous system. NGFR p75 plays a central role in the regulation of cell number by apoptosis in the developing CNS.

ALT Names :

CD271 antigen;Low affinity neurotrophin receptor p75NTR;Low-affinity nerve growth factor receptor;NGF receptor;low affinity nerve growth factor receptor;nerve growth factor receptor;nerve growth factor receptor (TNFR superfamily, member 16);p75 ICD

Immunogen :

Extracellular fragment generated from sequences from the third exon of mouse p75 (amino acids 43-161).

Specificity :

p75 nerve growth factor receptor (p75 Neurotrophin receptor, low affinity neurotrophin receptor), extracellular domain.

Package Size :

100 µL

Uses :

Flow Cytometry;Immunocytochemistry;Immunofluorescence;Immunohistochemistry;Immunohistochemistry (Paraffin);Immunoprecipitation;Affects Function;Western Blotting

Storage :

Stable for 1 year at -20ºC from date of receipt.