Synapsin I Antibody | EMD Millipore AB1543 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Synapsin I Antibody

catalog :

AB1543

quantity :

50 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other

citations: 21

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:2000; loading ...; fig 5d	Zhu C, Li B, Frontzek K, Liu Y, Aguzzi A. SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease. J Exp Med. 2019;216:743-756 pubmed publisher
other; rat; loading ...; fig 5c	Ganguly A, Han X, Das U, Wang L, Loi J, Sun J, et al. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin. J Cell Biol. 2017;216:2059-2074 pubmed publisher
immunocytochemistry; rat; 1:500; loading ...; fig 2b	Fowler D, Peters J, Williams C, Washbourne P. Redundant Postsynaptic Functions of SynCAMs 1-3 during Synapse Formation. Front Mol Neurosci. 2017;10:24 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:200; fig s3	Vasek M, Garber C, Dorsey D, Durrant D, Bollman B, Soung A, et al. A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature. 2016;534:538-43 pubmed publisher
immunocytochemistry; human; 1:500; fig 8	Rosiak K, Smolarz M, Stec W, Peciak J, Grzela D, Winiecka Klimek M, et al. IDH1R132H in Neural Stem Cells: Differentiation Impaired by Increased Apoptosis. PLoS ONE. 2016;11:e0154726 pubmed publisher
immunocytochemistry; human; fig 2	Kim E, Jeon C, Lee S, Hwang I, Chung T. Robust Type-specific Hemisynapses Induced by Artificial Dendrites. Sci Rep. 2016;6:24210 pubmed publisher
western blot; mouse; fig 2	Hayashi Y, Nishimune H, Hozumi K, Saga Y, Harada A, Yuzaki M, et al. A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons. Sci Rep. 2016;6:23969 pubmed publisher
	Gao L, Zhang Z, Lu J, Pei G. Mitochondria Are Dynamically Transferring Between Human Neural Cells and Alexander Disease-Associated GFAP Mutations Impair the Astrocytic Transfer. Front Cell Neurosci. 2019;13:316 pubmed publisher
	Salissou M, Mahaman Y, Zhu F, Huang F, Wang Y, Xu Z, et al. Methanolic extract of Tamarix Gallica attenuates hyperhomocysteinemia induced AD-like pathology and cognitive impairments in rats. Aging (Albany NY). 2018;10:3229-3248 pubmed publisher
	McDermott J, Goldblatt D, Paradis S. Class 4 Semaphorins and Plexin-B receptors regulate GABAergic and glutamatergic synapse development in the mammalian hippocampus. Mol Cell Neurosci. 2018;92:50-66 pubmed publisher
	Li Y, Kim R, Cho Y, Song W, Kim D, Kim K, et al. Lrfn2-Mutant Mice Display Suppressed Synaptic Plasticity and Inhibitory Synapse Development and Abnormal Social Communication and Startle Response. J Neurosci. 2018;38:5872-5887 pubmed publisher
	Koeppen J, Nguyen A, Nikolakopoulou A, Garcia M, Hanna S, Woodruff S, et al. Functional Consequences of Synapse Remodeling Following Astrocyte-Specific Regulation of Ephrin-B1 in the Adult Hippocampus. J Neurosci. 2018;38:5710-5726 pubmed publisher
	Krukowski K, Feng X, Paladini M, Chou A, Sacramento K, Grue K, et al. Temporary microglia-depletion after cosmic radiation modifies phagocytic activity and prevents cognitive deficits. Sci Rep. 2018;8:7857 pubmed publisher
	Liu Z, Zhang C, Skamagki M, Khodadadi Jamayran A, Zhang W, Kong D, et al. Elevated p53 Activities Restrict Differentiation Potential of MicroRNA-Deficient Pluripotent Stem Cells. Stem Cell Reports. 2017;9:1604-1617 pubmed publisher
	Tang Y, Lin Y, Ni H, Dong J, Yuan H, Zhang Y, et al. Inhibiting Histone Deacetylase 2 (HDAC2) Promotes Functional Recovery From Stroke. J Am Heart Assoc. 2017;6: pubmed publisher
	Ye Z, Goutman J, Pyott S, Glowatzki E. mGluR1 enhances efferent inhibition of inner hair cells in the developing rat cochlea. J Physiol. 2017;595:3483-3495 pubmed publisher
	Holt J, Jordan P, Lysakowski A, Shah A, Barsz K, Contini D. Muscarinic Acetylcholine Receptors and M-Currents Underlie Efferent-Mediated Slow Excitation in Calyx-Bearing Vestibular Afferents. J Neurosci. 2017;37:1873-1887 pubmed publisher
	Abraira V, Kuehn E, Chirila A, Springel M, Toliver A, Zimmerman A, et al. The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn. Cell. 2017;168:295-310.e19 pubmed publisher
	Lin Y, Wang H, Huang D, Hsieh P, Lin M, Chou C, et al. Neuronal Splicing Regulator RBFOX3 (NeuN) Regulates Adult Hippocampal Neurogenesis and Synaptogenesis. PLoS ONE. 2016;11:e0164164 pubmed publisher
	Tian T, Sun Y, Wu H, Pei J, Zhang J, Zhang Y, et al. Acupuncture promotes mTOR-independent autophagic clearance of aggregation-prone proteins in mouse brain. Sci Rep. 2016;6:19714 pubmed publisher
	Leinders Zufall T, Ishii T, Chamero P, Hendrix P, Oboti L, Schmid A, et al. A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons. J Neurosci. 2014;34:5121-33 pubmed publisher

product information

Catalog Number :

AB1543

Subcategory :

Neuroscience

Product Name :

Anti-Synapsin I Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P17600

Host Name :

Rabbit

Antigen :

Synapsin I

Conjugate :

Serum

Product Description :

Anti-Synapsin I Antibody

Cross Reactivity :

Bovine;Human;Mouse;Rat

Background :

Synapsin I is a member of the synapsin family. Synapsins are neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations of the Synapsin I gene may be associated with X linked disorders with primary neuronal degeneration such as Rett syndrome.

ALT Names :

Synapsin-1

Immunogen :

Synapsin I (mixture of Ia & Ib) purified from bovine brain.

Specificity :

Synapsin I (Mr of 80,000 and 77,000). Immunolabeling is blocked by preadsorption of antibody with Synapsin I. Synapsin is located only in brain nerve terminal and is an excellent marker for synapses.

Package Size :

50 µL

Uses :

Immunocytochemistry;Immunohistochemistry (Paraffin);Immunoprecipitation;Western Blotting

Storage :

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.