zDHHC8 Antibody | EMD Millipore AB15242 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

zDHHC8 Antibody

catalog :

AB15242

quantity :

100 µg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dog, chicken

application :

western blot

product information

Catalog Number :

AB15242

Subcategory :

Neuroscience

Product Name :

Anti-zDHHC8 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q9ULC8

Host Name :

Rabbit

Antigen :

zDHHC8

Conjugate :

Affinity Purified

Product Description :

Anti-zDHHC8 Antibody

Cross Reactivity :

Human;Rat

Background :

Six genes in the 1.5 Mb region of chromosome 22 deleted in DiGeorge/22q11 deletion syndrome–Mrpl40, Prodh, Slc25a1, Txnrd2, T10, and Zdhhc8–encode mitochondrial proteins. All six genes are expressed in the brain, and maximal expression coincides with peak forebrain synaptogenesis shortly after birth. Furthermore, their protein products are associated with brain mitochondria, including those in synaptic terminals. Among the six, only Zddhc8 influences mitochondria-regulated apoptosis when overexpressed, and appears to interact biochemically with established mitochondrial proteins. Zdhhc8 has an apparent interaction with Uqcrc1, a component of mitochondrial complex III. The two proteins are coincidently expressed in pre-synaptic processes; however, Zdhhc8 is more frequently seen in glutamatergic terminals (1).

ALT Names :

Zinc finger DHHC domain-containing protein 8;Zinc finger protein 378 ;membrane-associated DHHC8 zinc finger protein;zinc finger, DHHC domain containing 8;zinc finger, DHHC domain like containing 1;zinc finger, DHHC-type containing 8

Immunogen :

Syntheic linear peptide.

Specificity :

Cat. AB15242 recognizes the C-terminus of zDHHC8.

Package Size :

100 µg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt. Handling Recommendations: Prior to removing the cap, gently centrifuge the vial and gently mix the solution.