Glutamate Receptor 4 Antibody | EMD Millipore AB1508 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Glutamate Receptor 4 Antibody

catalog :

AB1508

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, chicken

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other, immunohistochemistry knockout validation

citations: 13

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry knockout validation; mouse; 1:300; loading ...; fig 1a	Evonuk K, Doyle R, Moseley C, Thornell I, Adler K, Bingaman A, et al. Reduction of AMPA receptor activity on mature oligodendrocytes attenuates loss of myelinated axons in autoimmune neuroinflammation. Sci Adv. 2020;6:eaax5936 pubmed publisher
immunohistochemistry; mouse; 1:400; loading ...; fig 6a	Lesperance L, Yang Y, Wang L. Delayed expression of activity-dependent gating switch in synaptic AMPARs at a central synapse. Mol Brain. 2020;13:6 pubmed publisher
other; mouse; 1:1000; loading ...; fig 1a western blot; human; fig s5a	Brechet A, Buchert R, Schwenk J, Boudkkazi S, Zolles G, Siquier Pernet K, et al. AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability. Nat Commun. 2017;8:15910 pubmed publisher
immunohistochemistry; mouse; 1:200; loading ...; tbl 1 western blot; mouse; 1:2000; loading ...; tbl 1	Adotevi N, Leitch B. Alterations in AMPA receptor subunit expression in cortical inhibitory interneurons in the epileptic stargazer mutant mouse. Neuroscience. 2016;339:124-138 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 4c	Park K, Ribic A, Laage Gaupp F, Coman D, Huang Y, Dulla C, et al. Excitatory Synaptic Drive and Feedforward Inhibition in the Hippocampal CA3 Circuit Are Regulated by SynCAM 1. J Neurosci. 2016;36:7464-75 pubmed publisher
	Taylor B, Sinha G, Donahue R, Grachen C, Morón J, Doolen S. Opioid receptors inhibit the spinal AMPA receptor Ca2+ permeability that mediates latent pain sensitization. Exp Neurol. 2019;314:58-66 pubmed publisher
	Angueyra J, Kindt K. Leveraging Zebrafish to Study Retinal Degenerations. Front Cell Dev Biol. 2018;6:110 pubmed publisher
	Kindt K, SHEETS L. Transmission Disrupted: Modeling Auditory Synaptopathy in Zebrafish. Front Cell Dev Biol. 2018;6:114 pubmed publisher
	Favuzzi E, Marques Smith A, Deogracias R, Winterflood C, Sánchez Aguilera A, Mantoan L, et al. Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican. Neuron. 2017;95:639-655.e10 pubmed publisher
	Barad Z, Grattan D, Leitch B. NMDA Receptor Expression in the Thalamus of the Stargazer Model of Absence Epilepsy. Sci Rep. 2017;7:42926 pubmed publisher
	Minbay Z, Serter Kocoglu S, Gok Yurtseven D, Eyigor O. Immunohistochemical localization of ionotropic glutamate receptors in the rat red nucleus. Bosn J Basic Med Sci. 2017;17:29-37 pubmed publisher
	Klooster J, Kamermans M. An Ultrastructural and Immunohistochemical Analysis of the Outer Plexiform Layer of the Retina of the European Silver Eel (Anguilla anguilla L). PLoS ONE. 2016;11:e0152967 pubmed publisher
	Erlenhardt N, Yu H, Abiraman K, Yamasaki T, Wadiche J, Tomita S, et al. Porcupine Controls Hippocampal AMPAR Levels, Composition, and Synaptic Transmission. Cell Rep. 2016;14:782-794 pubmed publisher

product information

Catalog Number :

AB1508

Subcategory :

Neuroscience

Product Name :

Anti-Glutamate Receptor 4 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P48058

Host Name :

Rabbit

Antigen :

Glutamate Receptor 4

Conjugate :

Affinity Purified

Product Description :

Anti-Glutamate Receptor 4 Antibody

Cross Reactivity :

Rat;Mouse

Background :

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG- CGG; QR- R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene.

ALT Names :

AMPA-selective glutamate receptor 4;Glutamate receptor ionotropic, AMPA 4 ;glutamate receptor 4;glutamate receptor, ionotrophic, AMPA 4

Immunogen :

Synthetic linear peptide.

Specificity :

Cat. # AB1508 recognizes C-Terminus of GluR4.

Package Size :

100 μg

Uses :

Immunohistochemistry (Paraffin);Immunocytochemistry;Immunohistochemistry;Immunoprecipitation;Western Blotting

Storage :

Stable for 1 year at 2-8ºC from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C.