Glutamate Receptor 2 & 3 Antibody | EMD Millipore AB1506 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Glutamate Receptor 2 & 3 Antibody

catalog :

AB1506

quantity :

50 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other

citations: 14

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 5a	Dierich M, Hartmann S, Dietrich N, Moeser P, Brede F, Johnson Chacko L, et al. β-Secretase BACE1 Is Required for Normal Cochlear Function. J Neurosci. 2019;39:9013-9027 pubmed publisher
immunohistochemistry - frozen section; mouse; fig 3u	Dias D, Kim H, Holl D, Werne Solnestam B, Lundeberg J, Carlen M, et al. Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury. Cell. 2018;173:153-165.e22 pubmed publisher
immunohistochemistry; mouse; fig ev2b	Vogl C, Butola T, Haag N, Hausrat T, Leitner M, Moutschen M, et al. The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing. EMBO Rep. 2017;18:2015-2029 pubmed publisher
western blot; mouse; 1:300; loading ...; fig 5c	Kilpatrick C, Murakami S, Feng M, Wu X, Lal R, Chen G, et al. Dissociation of Golgi-associated DHHC-type Zinc Finger Protein (GODZ)- and Sertoli Cell Gene with a Zinc Finger Domain-? (SERZ-?)-mediated Palmitoylation by Loss of Function Analyses in Knock-out Mice. J Biol Chem. 2016;291:27371-27386 pubmed publisher
immunocytochemistry; mouse; 1:200; loading ...; tbl 1	Adotevi N, Leitch B. Alterations in AMPA receptor subunit expression in cortical inhibitory interneurons in the epileptic stargazer mutant mouse. Neuroscience. 2016;339:124-138 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 7e	Lauritzen K, Hasan Olive M, Regnell C, Kleppa L, Scheibye Knudsen M, Gjedde A, et al. A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain. Neurobiol Aging. 2016;48:34-47 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 8a	Lazarczyk M, Kemmler J, Eyford B, Short J, Varghese M, Sowa A, et al. Major Histocompatibility Complex class I proteins are critical for maintaining neuronal structural complexity in the aging brain. Sci Rep. 2016;6:26199 pubmed publisher
other; rat; 1:30; loading ...; fig 6a	Hussain S, Ringsevjen H, Egbenya D, Skjervold T, Davanger S. SNARE Protein Syntaxin-1 Colocalizes Closely with NMDA Receptor Subunit NR2B in Postsynaptic Spines in the Hippocampus. Front Mol Neurosci. 2016;9:10 pubmed publisher
	Pernía M, Diaz I, Colmenárez Raga A, Rivadulla C, Cudeiro J, Plaza I, et al. Cross-modal reaction of auditory and visual cortices after long-term bilateral hearing deprivation in the rat. Brain Struct Funct. 2020;225:129-148 pubmed publisher
	Koeppen J, Nguyen A, Nikolakopoulou A, Garcia M, Hanna S, Woodruff S, et al. Functional Consequences of Synapse Remodeling Following Astrocyte-Specific Regulation of Ephrin-B1 in the Adult Hippocampus. J Neurosci. 2018;38:5710-5726 pubmed publisher
	Favuzzi E, Marques Smith A, Deogracias R, Winterflood C, Sánchez Aguilera A, Mantoan L, et al. Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican. Neuron. 2017;95:639-655.e10 pubmed publisher
	GoodSmith D, Chen X, Wang C, Kim S, Song H, Burgalossi A, et al. Spatial Representations of Granule Cells and Mossy Cells of the Dentate Gyrus. Neuron. 2017;93:677-690.e5 pubmed publisher
	Danielson N, Turi G, Ladow M, Chavlis S, Petrantonakis P, Poirazi P, et al. InÂ Vivo Imaging of Dentate Gyrus Mossy Cells in Behaving Mice. Neuron. 2017;93:552-559.e4 pubmed publisher
	Boillot M, Lee C, Allene C, LeGuern E, Baulac S, Rouach N. LGI1 acts presynaptically to regulate excitatory synaptic transmission during early postnatal development. Sci Rep. 2016;6:21769 pubmed publisher

product information

Catalog Number :

AB1506

Subcategory :

Neuroscience

Product Name :

Anti-Glutamate Receptor 2 & 3 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P42262

Host Name :

Rabbit

Antigen :

Glutamate Receptor 2 & 3

Conjugate :

Affinity Purified

Product Description :

Anti-Glutamate Receptor 2 & 3 Antibody

Cross Reactivity :

Human;Rat;Mouse;Monkey;Guinea Pig;Hamster;Gerbil

Background :

Glutamate receptors (GluRs) can be categorized as ionotropic or metabotropic and subcategorized by their agonist preferences (NMDA, AMPA or Kainic acid). There are four types of AMPA selective GluR subunits (GluR1, GluR2, GluR3 and GluR4). Tetrameric or pentameric combinations of different subunits contributes to the functional diversity of AMPA receptors. In general, AMPA receptors mediate fast synaptic current at most excitatory synapses, with stoichiometry characterized by subtype composition.

ALT Names :

AMPA-selective glutamate receptor 2;AMPA-selective glutamate receptor 2;glutamate receptor 2;glutamate receptor, ionotropic, AMPA 2

Immunogen :

Carboxy terminus peptide of rat GluR2 conjugated to BSA with glutaraldehyde (EGYNVYGIESVKI).

Specificity :

It recognizes both GluR2 and GluR3 which have nearly identical carboxy terminal sequences. Western blot analysis of rat brain shows two poorly separated bands which comigrate with GluR2 and GluR3 expressed in transfected cells. GluR2 migrates slightly ahead of GluR3. No cross-reaction with GluR1 or GluR4. The antibody appears to recognize GluR 2 & 3 in several other species, but has not been extensively characterized in these cases.

Package Size :

50 µg

Uses :

Immunohistochemistry (Paraffin);Immunocytochemistry;Immunohistochemistry;Immunoprecipitation;Western Blotting

Storage :

Maintain lyophilized material at +2-8°C or -20°C for up to 6 months after date of receipt. Reconstitute to 500 μL with sterile distilled water. Store reconstituted material frozen (-20°C or -80°C) in undiluted aliquots for up to six months. Diluted antibody containing 0.1% sodium azide for Western blot analysis can be stored for several weeks at +2-8°C and reused repeatedly. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.