This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Tbr1 Antibody
catalog :
AB10554
quantity :
100 μg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, dogs, bovine
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 5
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:400; loading ...; fig 1k
Roy A, Murphy R, Deng M, MacDonald J, Bammler T, Aldinger K, et al. PI3K-Yap activity drives cortical gyrification and hydrocephalus in mice. elife. 2019;8: pubmed publisher
  • immunocytochemistry; human; loading ...; fig s3a
Zeltner N, Fattahi F, Dubois N, Saurat N, Lafaille F, Shang L, et al. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia. Nat Med. 2016;22:1421-1427 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s6a, b
Huang Z, Hu J, Pan J, Wang Y, Hu G, Zhou J, et al. YAP stabilizes SMAD1 and promotes BMP2-induced neocortical astrocytic differentiation. Development. 2016;143:2398-409 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:2000
Gouty Colomer L, Hosseini B, Marcelo I, Schreiber J, Slump D, Yamaguchi S, et al. Arc expression identifies the lateral amygdala fear memory trace. Mol Psychiatry. 2016;21:364-75 pubmed publisher
Docampo Seara A, Lanoizelet M, Lagadec R, Mazan S, Candal E, Rodriguez M. Mitral cell development in the olfactory bulb of sharks: evidences of a conserved pattern of glutamatergic neurogenesis. Brain Struct Funct. 2019;: pubmed publisher
product information
Catalog Number :
AB10554
Subcategory :
Neuroscience
Product Name :
Anti-Tbr1 Antibody
Product Type :
Antibodies
Clonality :
Polyclonal Antibody
Gene ID :
Q64336
Host Name :
Rabbit
Antigen :
Tbr1
Conjugate :
Affinity Purified
Product Description :
Anti-Tbr1 Antibody
Cross Reactivity :
Mouse;Rat;Horse;Pig;Opossum;Bovine;Canine
Background :
Tbr1 gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Tbr1, a putative transcription factor known to be expressed in post-mitotic neurons, has been found highly expressed in glutamatergic early-born cortical neurons. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region the Tbr1 derived protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
ALT Names :
T-box, brain, 1;T-brain-1;T-box brain protein 1
Immunogen :
KLH-conjugated linear peptide corresponding to mouse Tbr1 near the N-terminus.
Package Size :
100 μg
Uses :
Immunohistochemistry (Paraffin)
Storage :
Stable for 1 year at 2-8°C from date of receipt
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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