Prohormone Convertase PC1/PC3 Antibody | EMD Millipore AB10553 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Prohormone Convertase PC1/PC3 Antibody

catalog :

AB10553

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, bovine

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:1000; loading ...; fig 8c	Santos M, Anderson C, Neschen S, Zumbrennen Bullough K, Romney S, Kahle Stephan M, et al. Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification. Nat Commun. 2020;11:296 pubmed publisher

product information

Catalog Number :

AB10553

Subcategory :

Neuroscience

Product Name :

Anti-Prohormone Convertase PC1/PC3 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P29120

Host Name :

Rabbit

Antigen :

Prohormone Convertase PC1/PC3

Conjugate :

Affinity Purified

Product Description :

Anti-Prohormone Convertase PC1/PC3 Antibody

Cross Reactivity :

Human;Mouse;Rat

Background :

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. The use of alternate polyadenylation sites has been found for this gene. Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known.

ALT Names :

NEC 1;Prohormone convertase 1 ;Proprotein convertase 1;neuroendocrine convertase 1;prohormone convertase 3;proprotein convertase subtilisin/kexin type 1

Immunogen :

This antibody is generated from rabbits immunized with a KLH conjugated linear peptide within human Prohormone Convertase PC1/PC3.

Specificity :

This antibody recognizes Prohormone Convertase PC1/PC3.

Package Size :

100 µg

Uses :

Western Blotting;Immunocytochemistry;Immunohistochemistry

Storage :

Maintain refrigerated at 2-8°C for up to 12 months.