VDAC Antibody | EMD Millipore AB10527 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

VDAC Antibody

catalog :

AB10527

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine, chimpanzee

application :

western blot

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:2,500; fig 4	Györffy B, Gulyassy P, Gellén B, Völgyi K, Madarasi D, Kis V, et al. Widespread alterations in the synaptic proteome of the adolescent cerebral cortex following prenatal immune activation in rats. Brain Behav Immun. 2016;56:289-309 pubmed publisher
	Petrie E, Sandow J, Jacobsen A, Smith B, Griffin M, Lucet I, et al. Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis. Nat Commun. 2018;9:2422 pubmed publisher
	Bowman C, Rodriguez S, Selen Alpergin E, Acoba M, Zhao L, Hartung T, et al. The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency. Cell Chem Biol. 2017;24:673-684.e4 pubmed publisher
	Conos S, Chen K, De Nardo D, Hara H, Whitehead L, NÃºÃ±ez G, et al. Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner. Proc Natl Acad Sci U S A. 2017;114:E961-E969 pubmed publisher
	Iyer S, Anwari K, Alsop A, Yuen W, Huang D, Carroll J, et al. Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies. Nat Commun. 2016;7:11734 pubmed publisher

product information

Catalog Number :

AB10527

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-VDAC Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P21796

Host Name :

Rabbit

Antigen :

VDAC

Conjugate :

Affinity Purified

Product Description :

Anti-VDAC Antibody

Cross Reactivity :

Human;Mouse;Rat;Bovine;Horse;Rhesus Macaque;Chimpanzee;Pig

Background :

Voltage-dependent anion-selective channel protein 1 (also known as VDAC, VDAC1 or outer mitochondrial membrane protein porin 1) is the the outer mitochondrial membrane receptor for hexokinase and BCL2L1. VDAC forms a channel through the mitochondrial membrane and is involved in small molecule diffusion, cell volume regulation and apoptosis. VDAC may participate in the formation of the permeability transition pore complex (PTPC), which is responsible for the release of mitochondrial products that triggers apoptosis.

ALT Names :

voltage-dependent anion channel 1;Porin 31HL;Outer mitochondrial membrane protein porin 1;PORIN-31-HL;Porin 31HM;voltage-dependent anion-selective channel protein 1;Plasmalemmal porin

Immunogen :

KLH-conjugated linear peptide corresponding to human VDAC.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt