NLK Antibody | EMD Millipore AB10206 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

NLK Antibody

catalog :

AB10206

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dogs, chicken

application :

western blot

citations: 1

Reference
Liu R, Khalil H, Lin S, Sargent M, York A, Molkentin J. Nemo-Like Kinase (NLK) Is a Pathological Signaling Effector in the Mouse Heart. PLoS ONE. 2016;11:e0164897 pubmed publisher

product information

Catalog Number :

AB10206

Subcategory :

Stem Cell Research

Product Name :

Anti-NLK Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q9UBE8

Host Name :

Rabbit

Antigen :

NLK

Conjugate :

Purified

Product Description :

Anti-NLK Antibody

Cross Reactivity :

Human;Mouse;Rat;Chicken;Canine;Xenopus

Background :

NLK, or nemo-like kinase, plays a role in cell fate determination and is required for the differentiation of bone marrow stromal cells, as it acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. Nlk has also been shown to suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. Recent studies indicate that NLK may also promote the survival of embryonic spinal neurons and sensory neurons.

ALT Names :

nemo like kinase ;Protein LAK1

Immunogen :

Synthetic human NLK peptide, a.a. 459-473.

Specificity :

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptided selected from human NLK.

Package Size :

100 µg

Uses :

Western Blotting

Storage :

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.