STAT3 Rabbit pAb | EMD Millipore 569388-100UL product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

STAT3 Rabbit pAb

catalog :

569388-100UL

quantity :

100 uL

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation

product information

Catalog Number :

569388-100UL

Category :

Antibodies

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-STAT3 Rabbit pAb

Product Type :

Antibodies

Clonality :

Polyclonal

Gene ID :

6774 (Hu), 20848 (Ms), 25125 (Rt)

Host Name :

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-STAT3 Rabbit pAb

Cross Reactivity :

Human, Mouse, Rat

Background :

STAT3 is activated by a variety of cytokines including interleukins, CNTF and EPO. Activation of STAT3 is accompanied by tyrosine phosphorylation at Tyr705 which induces dimerization, nuclear translocation and DNA binding. Transcriptional activation also appears to be regulated by serine phosphorylation (Ser727) probably via MAP-like kinases. As phosphorylation of STAT3 at Tyr705 is essential for dimerization and DNA binding, phosphorylation at this site is an excellent marker of STAT3 activity.

ALT Names :

acute-phase response factor, APRF, Stat3 alpha, Stat3 alpha isoform, Stat3 beta isoform, Stat3 delta, signal transducer and activator of transcription 3 (acute-phase response factor)

Immunogen :

a synthetic peptide corresponding to amino acids surrounding Tyr 705 of mouse STAT3

Specificity :

Recognizes the ~90 kDa STAT3 protein.

Package Size :

100 uL

Uses :

WB, IP, IH(P)

Storage :

Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.