This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
PhosphoDetect™ Anti-Smad2 (pSer465/467) Rabbit pAb
catalog :
566415-50UL
quantity :
50 uL
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot
product information
Catalog Number :
566415-50UL
Category :
Antibodies
Subcategory :
Epigenetics & Nuclear Function
Product Name :
PhosphoDetect™ Anti-Smad2 (pSer465/467) Rabbit pAb
Product Type :
Antibodies
Clonality :
Polyclonal
Gene ID :
4087 (Hu), 17126 (Ms), 29357 (Rt)
Host Name :
Rb
Conjugate :
Purified
Isotype :
IgG
Product Description :
PhosphoDetect™ Anti-Smad2 (pSer465/467) Rabbit pAb
Cross Reactivity :
Human, Mink, Mouse
Background :
The MAD-related (MADR) family of proteins are intracellular signaling components for the TGFbeta superfamily of ligands. Smad2 is activated by phosphorylation by the TGFbeta/activin receptor. Activated Smad2 forms a heterocomplex with Smad4 that is then translocated into the nucleus, where it associates with other transcription factors and regulates expression of ligand-responsive genes. Both Smad2 and its closely related homolog Smad3 act as latent nuclear transcriptional activators and mediate intracellular signaling by TGF-betas and activin.
ALT Names :
hMAD-2, hSMAD2, JV18, JV18-1, MADH2, MADR2, MGC156656, MGC22139, MGC34440, SMAD family member 2
Immunogen :
a synthetic phosphopeptide surrounding the Ser 465 and Ser 467 phosphorylation sites of human Smad2
Specificity :
Recognizes the ~58 kDa Smad2 protein phosphorylated at Ser 465/467 .
Package Size :
50 uL
Uses :
WB
Storage :
Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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