PhosphoDetect™ Anti-SAPK/JNK (pThr183, Tyr185) Rabbit pAb | EMD Millipore 559309-10T product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PhosphoDetect™ Anti-SAPK/JNK (pThr183, Tyr185) Rabbit pAb

catalog :

559309-10T

quantity :

10 test

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 2c	Gómez Puerto M, Verhagen L, Braat A, Lam E, Coffer P, Lorenowicz M. Activation of autophagy by FOXO3 regulates redox homeostasis during osteogenic differentiation. Autophagy. 2016;12:1804-1816 pubmed

product information

Catalog Number :

559309-10T

Category :

Antibodies

Subcategory :

Cell Signaling

Product Name :

PhosphoDetect™ Anti-SAPK/JNK (pThr183, Tyr185) Rabbit pAb

Product Type :

Antibodies

Clonality :

Polyclonal

Gene ID :

5599 (Hu), 26419 26420 (Ms), 116554 50658 (Rt)

Host Name :

Conjugate :

Purified

Isotype :

IgG

Product Description :

PhosphoDetect™ Anti-SAPK/JNK (pThr183, Tyr185) Rabbit pAb

Cross Reactivity :

c. Elegans , Chicken, drosophila , Human, Mouse, Rat

Background :

C-Jun-N-terminal kinase (JNK), also called stress-activated protein kinase (SAPK) is a member of the mitogen activated protein kinase (MAPK) family. JNK is activated in response to various extracellular stimuli, including pro-inflammatory cytokines. Phosphorylation of threonine and tyrosine in the Thr-Pro-Tyr domain is required for full activation. Mitogen activated protein kinase kinase (MKK4) preferentially phosphorylates tyrosine 185, and MKK7 causes preferential phosphorylation of threonine 183.

ALT Names :

C-JUN N-TERMINAL KINASE1, JNK, JNK1, JNK1 PROTEIN KINASE, JNK1A2, JNK21B1/2, Sapk gamma, SAPK P46, SAPK1, SAPK1/JNK, STRESS-ACTIVATED PROTEIN KINASE-LIKE KINASE, Jnk p54, Jnk p55, JNK-55, JUNKINASE, p54a, PRKM9, SAPK, SAPK ALPHA, SAPK ALPHA 1, mitogen-activated protein kinase 8

Immunogen :

a synthetic phosphopeptide corresponding to amino acids surrounding the Thr 183 and Tyr 185 phosphorylation sites of human SAPK/JNK

Specificity :

Recognizes the ~49 kDa JNK1/SAPK1 protein and the ~55 kDa JNK2/SAPK2 protein phosphorylated at Thr 183 and Tyr 185 .

Package Size :

10 test

Uses :

WB, IH

Storage :

Following initial thaw, aliquot and freeze (-70°C). Avoid repeated freeze-thaw.