SAPK/JNK Rabbit pAb | EMD Millipore 559304-200UL product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SAPK/JNK Rabbit pAb

catalog :

559304-200UL

quantity :

200 uL

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

product information

Catalog Number :

559304-200UL

Category :

Antibodies

Subcategory :

Cell Signaling

Product Name :

Anti-SAPK/JNK Rabbit pAb

Product Type :

Antibodies

Clonality :

Polyclonal

Gene ID :

5601 (Hu), 26420 (Ms), 50658 (Rt)

Host Name :

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-SAPK/JNK Rabbit pAb

Cross Reactivity :

Human, Mouse, Rat

Background :

The Stress-activated protein kinases (SAPK), also referred to as Jun N-terminal kinases (JNK), function in a protein kinase cascade transducing cellular stress signals. SAPK/JNKs are activated by a highly diverse group of extracellular signals, including UV light, inflammatory cytokines and a wide variety of cellular stresses. Activation occurs via phosphorylation at Thr183 and Tyr185 by the dual specificity enzyme SEK/MKK4 and as yet unidentified kinases. Since dual phosphorylation of SAPK/JNK at Thr183/Tyr185 is essential for kinase activity, phosphorylation at this site is an excellent marker of SAPK/JNK activity. Activated SAPK in turn phosphorylates and activates several transcription factors, including c-jun at Ser63/73 and ATF-2 at Ser69/71.

ALT Names :

AI851083, Jnk p54, Jnk p55, JNK-55, JNK2, JNK2A, Jnk2a2, JNK2ALPHA, JNK2B, JNK2BETA, JUNKINASE, p54a, p54aSAPK, PRKM9, SAPK, SAPK ALPHA, SAPK ALPHA 1, mitogen-activated protein kinase 9

Immunogen :

a full-length, recombinant, human p54 SAPK/JNK2 fusion protein

Specificity :

Recognizes the ~54 kDa SAPK/JNK protein.

Package Size :

200 uL

Uses :

WB, IC

Storage :

Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.