Mast Cell Tryptase Mouse mAb (AA1) | EMD Millipore 444905-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Mast Cell Tryptase Mouse mAb (AA1)

catalog :

444905-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunohistochemistry

product information

Catalog Number :

444905-100UG

Category :

Antibodies

Subcategory :

Inflammation & Immunology

Product Name :

Anti-Mast Cell Tryptase Mouse mAb (AA1)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

7177 (Hu), 17230 (Ms), 54271 (Rt)

Host Name :

Clone :

AA1

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Mast Cell Tryptase Mouse mAb (AA1)

Cross Reactivity :

Canine, Feline, Human, Monkey

Background :

Mast cells are tissue bound cells that normally are distributed throughout connective tissues. They are involved in inflammatory processes as important effector and regulatory cells. Mast cells are known to accumulate at sites of inflammation, such as asthma, allergic rhinitis, and rheumatoid arthritis. Mast cells contain preformed chemical mediators including histamine, chymase, carboxypeptidase and proteolytic tryptase. Mast cells of the skin and lung contain large amounts of tryptase, suggesting this enzyme has a major role in mast cell-mediated events. Human mast cell tryptase has the potential to be used as marker for mast cell activation and as a mediator of inflammation.

ALT Names :

Mcp-7, MCPT7, MMCP-7, TPS1, TPS2, TPSB1, TRYPTASE ALPHA, tryptase alpha/beta 1

Immunogen :

native, human mast cell, tryptase

Specificity :

Recognizes the ~32-38 kDa alpha- and beta-isoforms of tryptase in mast cells.

Package Size :

100 ug

Uses :

IH, WB, IH(P)

Storage :

Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.