Heme Oxygenase-1 Mouse mAb (HO-1-1) | EMD Millipore 374087-200UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Heme Oxygenase-1 Mouse mAb (HO-1-1)

catalog :

374087-200UG

quantity :

200 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

product information

Catalog Number :

374087-200UG

Category :

Antibodies

Subcategory :

Metabolism

Product Name :

Anti-Heme Oxygenase-1 Mouse mAb (HO-1-1)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

3162 (Hu), 15368 (Ms), 24451 (Rt)

Host Name :

Clone :

HO-1-1

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Heme Oxygenase-1 Mouse mAb (HO-1-1)

Cross Reactivity :

Bovine, Canine, Human, Monkey, Mouse, Rat

Background :

Heme oxygenase (HO) is a microsomal enzyme that oxidatively cleaves heme, a pro-oxidant, into carbon monoxide and biliverdin, which is reduced to the antioxidant, bilirubin. Two isozymes, termed HO-1 and HO-2, have been identified in rat, rabbit, monkey, and human tissues. By SDS-PAGE, mammalian HO-1 is ~31-33 kDa; HO-2 is ~36 kDa. HO-1, also referred to as stress protein Hsp32, is the inducible form of the enzyme. Expression of HO-1 can be induced by a variety of stimuli such as heme, metals, hormones, UV radiation and sulfhydryl depleting agents. In contrast, HO-2 is the constitutive form of the enzyme. HO-2 is the most prevalent form in most tissues, except the spleen where HO-1 levels are predominant.

ALT Names :

bK286B10, D8Wsu38e, HEME OXYGENASE, HEME OXYGENASE (DECYCLIZING) 1, HEME OXYGENASE-1, Hemox, Heox, HEOXG, Hmox, HO-1, HSP32, heme oxygenase (decycling) 1

Immunogen :

a synthetic peptide (MERPQPDSMPQDLSEALKEATKEVHTQAEN) corresponding to amino acids 1-30 of human HO-1 prepared as a four-branched multiple antigen peptide

Specificity :

Recognizes the ~32 kDa heme oxygenase (HO-1) protein.

Package Size :

200 ug

Uses :

WB, IC, IP

Storage :

Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.