GSK-3b Inhibitor XXV (GSK-3beta) Calbiochem 10 MG | EMD Millipore 361568-10MG product information

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product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

chemical

product name :

GSK-3b Inhibitor XXV (GSK-3beta) Calbiochem 10 MG

catalog :

361568-10MG

quantity :

10 MG

product information

Category :

Phosphorylation & Dephosphorylation

Catalog Number :

361568-10MG

Product Name :

GSK-3b Inhibitor XXV (GSK-3beta) Calbiochem 10 MG

Product Type :

Inhibitors

Product Description :

GSK-3b Inhibitor XXV (GSK-3beta) Calbiochem 10 MG

Background :

A blood brain barrier permeable oxadiazole compound that acts as a potent, reversible and ATP-competitive inhibitor of GSK-3beta activity (IC50 = 17.1 nM) with excellent selectivity over Cdk2 (22% inhibition at 10 uM). Shown to elevate liver glycogen levels by ~3.5- and ~4.3-fold in C57BL/6N mice when dosed at 5 and 15 mg/kg (i.p.) amounts.

ALT Names :

M SEW00923SC, N-(3-Chloro-4-methylphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazol-2-amine , 5-(4-Nitrophenyl)-N-(3-chloro-4-methyl)phenyl-1,3,4-oxadiazol-2-amine

Specificity :

White powder. Packaged under inert gas.

Purity :

≥99% by HPLC

Package Size :

10 MG

Storage :

+2°C to +8°C. Protect from light. Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up 6 months at -20°C.