Calnexin, C-Terminal (575-593) Rabbit pAb | EMD Millipore 208880-50UL product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Calnexin, C-Terminal (575-593) Rabbit pAb

catalog :

208880-50UL

quantity :

50 uL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:2000; fig 3	Seiferling D, Szczepanowska K, Becker C, Senft K, Hermans S, Maiti P, et al. Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt. EMBO Rep. 2016;17:953-64 pubmed publisher

product information

Catalog Number :

208880-50UL

Category :

Antibodies

Subcategory :

Neuroscience

Product Name :

Anti-Calnexin, C-Terminal (575-593) Rabbit pAb

Product Type :

Antibodies

Clonality :

Polyclonal

Gene ID :

821 (Hu), 12330 (Ms), 29144 (Rt)

Host Name :

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-Calnexin, C-Terminal (575-593) Rabbit pAb

Cross Reactivity :

Bovine, Canine, Guinea Pig, Hamster, Human, Monkey, Mouse, Rabbit, Rat, Sheep

Background :

Calnexin is an ER transmembrane protein that transiently associates with newly synthesized, incompletely folded monomeric glycoproteins. Calnexin associates with the ER membrane phosphoglycoprotein, signal sequence receptor SSRmu, and has been identified as the ER protein associated with major histocompatibility complex (MHC) class I heavy chain and with the T-cell receptor and membrane immunoglobulin before assembly of these multimeric complexes. Hence, calnexin may represent a molecular chaperone in the ER membrane that is selective for incompletely folded oligomeric membrane proteins newly translocated to the ER.

ALT Names :

CALNEXIN, Cell adhesion molecule with homology to l1cam precursor, CNX, D11Ertd153e, FLJ26570, IP90, P90, Similar to calnexin, calnexin

Immunogen :

a synthetic peptide (AEEDEILNRSPRNRKPRRE) corresponding to amino acids 575-593 of canine calnexin, conjugated to KLH

Specificity :

Recognizes the ~90 kDa calnexin protein.

Package Size :

50 uL

Uses :

Storage :

Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.