ChIPAb+ REST - ChIP Validated Antibody and Primer Set | EMD Millipore 17-641 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

ChIPAb+ REST - ChIP Validated Antibody and Primer Set

catalog :

17-641

quantity :

25 assays

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunoprecipitation, EMSA, chromatin immunoprecipitation, ChIP-Seq

citations: 5

Published Application/Species/Sample/Dilution	Reference
ChIP-Seq; human; loading ...; fig 6a	Chang Y, Lin T, Campbell M, Pan C, Lee S, Lee H, et al. REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer. Sci Rep. 2017;7:42795 pubmed publisher
chromatin immunoprecipitation; mouse; 1:2000; loading ...; fig 2a EMSA; mouse; loading ...; fig 3b	Zhang D, Wu B, Wang P, Wang Y, Lu P, Nechiporuk T, et al. Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts. Nucleic Acids Res. 2017;45:3102-3115 pubmed publisher
chromatin immunoprecipitation; mouse; fig 4	Paonessa F, Criscuolo S, Sacchetti S, Amoroso D, Scarongella H, Pecoraro Bisogni F, et al. Regulation of neural gene transcription by optogenetic inhibition of the RE1-silencing transcription factor. Proc Natl Acad Sci U S A. 2016;113:E91-100 pubmed publisher
	Saha D, Singh A, Hussain T, Srivastava V, Sengupta S, Kar A, et al. Epigenetic suppression of human telomerase (hTERT) is mediated by the metastasis suppressor NME2 in a G-quadruplex-dependent fashion. J Biol Chem. 2017;292:15205-15215 pubmed publisher
	Lim J, Ibaseta A, Fischer M, Cancilla B, O Young G, Cristea S, et al. Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. Nature. 2017;545:360-364 pubmed publisher

product information

Catalog Number :

17-641

Subcategory :

Epigenetics & Nuclear Function

Product Name :

ChIPAb+ REST - ChIP Validated Antibody and Primer Set

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q13127

Host Name :

Rabbit

Antigen :

REST

Conjugate :

Affinity Purified

Product Description :

ChIPAb+ REST - ChIP Validated Antibody and Primer Set

Cross Reactivity :

Human;Mouse;Rat

ALT Names :

Neural-restrictive silencer factor ;RE1-silencing transcription factor ;X2 box repressor;neuron restrictive silencer factor ;repressor binding to the X2 box

Immunogen :

The REST purified antibody is made against a GST fusion protein corresponding to amino acids 801-1097 of human REST.

Specificity :

Recognizes REST, Mr 120-200 kDa.

Package Size :

25 assays

Uses :

Western Blotting;Immunoprecipitation;Chromatin Immunoprecipitation (ChIP);ChIP-seq

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.