This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
ChIPAb+ Trimethyl-Histone H3 (Lys27) - ChIP Validated Antibody and Primer Set
catalog :
17-622
quantity :
25 assays
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, chromatin immunoprecipitation, ChIP-Seq
citations: 18
Published Application/Species/Sample/DilutionReference
  • ChIP-Seq; mouse; loading ...; fig 2e
  • chromatin immunoprecipitation; mouse; loading ...; fig 5c
Li F, Zeng Z, Xing S, Gullicksrud J, Shan Q, Choi J, et al. Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf. Nat Commun. 2018;9:5452 pubmed publisher
  • ChIP-Seq; mouse; fig 2d
Kazakevych J, Sayols S, Messner B, Krienke C, Soshnikova N. Dynamic changes in chromatin states during specification and differentiation of adult intestinal stem cells. Nucleic Acids Res. 2017;45:5770-5784 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 7b
Schauwecker S, Kim J, Licht J, Clevenger C. Histone H1 and Chromosomal Protein HMGN2 Regulate Prolactin-induced STAT5 Transcription Factor Recruitment and Function in Breast Cancer Cells. J Biol Chem. 2017;292:2237-2254 pubmed publisher
Lleres D, Moindrot B, Pathak R, Piras V, Matelot M, Pignard B, et al. CTCF modulates allele-specific sub-TAD organization and imprinted gene activity at the mouse Dlk1-Dio3 and Igf2-H19 domains. Genome Biol. 2019;20:272 pubmed publisher
Rodríguez Carballo E, Lopez Delisle L, Yakushiji Kaminatsui N, Ullate Agote A, Duboule D. Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes. BMC Biol. 2019;17:55 pubmed publisher
Schmidleithner L, Thabet Y, Schönfeld E, Köhne M, Sommer D, Abdullah Z, et al. Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction. Immunity. 2019;50:1232-1248.e14 pubmed publisher
Qu D, Sun W, Li L, Ma L, Sun L, Jin X, et al. Long noncoding RNA MALAT1 releases epigenetic silencing of HIV-1 replication by displacing the polycomb repressive complex 2 from binding to the LTR promoter. Nucleic Acids Res. 2019;47:3013-3027 pubmed publisher
Dudakovic A, Camilleri E, Paradise C, Samsonraj R, Gluscevic M, Paggi C, et al. Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice. J Biol Chem. 2018;293:12894-12907 pubmed publisher
Rodrigues P, Patel S, Harewood L, Olan I, Vojtasova E, Syafruddin S, et al. NF-κB-Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma Metastasis. Cancer Discov. 2018;8:850-865 pubmed publisher
Wan C, Liu X, Bai B, Cao H, Li H, Zhang Q. Regulation of the expression of tumor necrosis factor‑related genes by abnormal histone H3K27 acetylation: Implications for neural tube defects. Mol Med Rep. 2018;17:8031-8038 pubmed publisher
Balog J, Goossens R, Lemmers R, Straasheijm K, van der Vliet P, Heuvel A, et al. Monosomy 18p is a risk factor for facioscapulohumeral dystrophy. J Med Genet. 2018;55:469-478 pubmed publisher
Sarrach S, Huang Y, Niedermeyer S, Hachmeister M, Fischer L, Gille S, et al. Spatiotemporal patterning of EpCAM is important for murine embryonic endo- and mesodermal differentiation. Sci Rep. 2018;8:1801 pubmed publisher
Wang H, Bender A, Wang P, Karaköse E, Inabnet W, Libutti S, et al. Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas. Nat Commun. 2017;8:767 pubmed publisher
Lamere S, Thompson R, Meng X, Komori H, Mark A, Salomon D. H3K27 Methylation Dynamics during CD4 T Cell Activation: Regulation of JAK/STAT and IL12RB2 Expression by JMJD3. J Immunol. 2017;199:3158-3175 pubmed publisher
Jeziorska D, Murray R, De Gobbi M, Gaentzsch R, Garrick D, Ayyub H, et al. DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease. Proc Natl Acad Sci U S A. 2017;114:E7526-E7535 pubmed publisher
Yan L, Wang Y, Liu J, Nie Y, Zhong X, Kan Q, et al. Alterations of Histone Modifications Contribute to Pregnane X Receptor-Mediated Induction of CYP3A4 by Rifampicin. Mol Pharmacol. 2017;92:113-123 pubmed publisher
Xia L, Huang W, Bellani M, Seidman M, Wu K, Fan D, et al. CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes. Cancer Cell. 2017;31:653-668.e7 pubmed publisher
Qi F, Liu X, Wu H, Yu X, Wei C, Huang X, et al. Long noncoding AGAP2-AS1 is activated by SP1 and promotes cell proliferation and invasion in gastric cancer. J Hematol Oncol. 2017;10:48 pubmed publisher
product information
Catalog Number :
17-622
Subcategory :
Epigenetics & Nuclear Function
Product Name :
ChIPAb+ Trimethyl-Histone H3 (Lys27) - ChIP Validated Antibody and Primer Set
Product Type :
Antibodies
Clonality :
Polyclonal Antibody
Gene ID :
Q16695
Host Name :
Rabbit
Antigen :
Trimethyl-Histone H3 (Lys27)
Conjugate :
Protein A Purified
Product Description :
ChIPAb+ Trimethyl-Histone H3 (Lys27) - ChIP Validated Antibody and Primer Set
Cross Reactivity :
Human;Mouse
ALT Names :
H3K27me3;Histone H3 (tri methyl K27)
Immunogen :
KLH-conjugated, synthetic 2X-branched peptide containing the sequence . AR(me3K)SAP. in which me3K corresponds to trimethyl-lysine at residue 27 of human Histone H3.
Specificity :
trimethyl-Histone H3 (Lys27)
Package Size :
25 assays
Uses :
Western Blotting;Chromatin Immunoprecipitation (ChIP)
Storage :
1 year at -20°C from date of shipment
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
  • • Cancer
  • • Nuclear Signaling
  • • Apoptosis
  • • Cardiovascular Disease
  • • Developmental Biology
  • • Metabolic Disease
  • • Neurodegenerative Disease
  • • Cell Biology
View all the new antibodies at www.emdmillipore.com.