ChIPAb+™ Histone H3.3 - ChIP Validated Antibody and Primer Set | EMD Millipore 17-10245 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

ChIPAb+™ Histone H3.3 - ChIP Validated Antibody and Primer Set

catalog :

17-10245

quantity :

25 assays

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, chromatin immunoprecipitation

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:800; loading ...; fig 2c	Zhou L, Baibakov B, Canagarajah B, Xiong B, Dean J. Genetic mosaics and time-lapse imaging identify functions of histone H3.3 residues in mouse oocytes and embryos. Development. 2017;144:519-528 pubmed publisher
	Gomes A, Ilter D, Low V, Rosenzweig A, Shen Z, Schild T, et al. Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization. Cancer Cell. 2019;36:402-417.e13 pubmed publisher

product information

Catalog Number :

17-10245

Subcategory :

Epigenetics & Nuclear Function

Product Name :

ChIPAb+™ Histone H3.3 - ChIP Validated Antibody and Primer Set

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P84243

Host Name :

Rabbit

Antigen :

Histone H3.3

Conjugate :

Affinity Purified

Product Description :

ChIPAb+™ Histone H3.3 - ChIP Validated Antibody and Primer Set

Cross Reactivity :

Human;Mouse

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. Histone variant H3.3 is typically enriched in active chromatin.

ALT Names :

Histone H3.3

Immunogen :

KLH-conjugated linear peptide corresponding to human Histone H3.3.

Specificity :

This antibody recognizes human Histone H3.

Package Size :

25 assays

Uses :

Dot Blot;Western Blotting;Chromatin Immunoprecipitation (ChIP)

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.