Rac1 Antibody, clone 23A8, Agarose conjugate | EMD Millipore 16-637 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Rac1 Antibody, clone 23A8, Agarose conjugate

catalog :

16-637

quantity :

200 μL

clonality :

monoclonal

host :

mouse

conjugate :

agarose

clone name :

23A8

The same clone is also sold as:

Abcam: ab33186
LifeSpan Biosciences: LS-C85408

reactivity :

human, mouse

application :

immunoprecipitation

citations: 2

Reference
Tang H, Talbot C, Fung M, Tang H. Molecular signature of anastasis for reversal of apoptosis. F1000Res. 2017;6:43 pubmed publisher
Nishita M, Itsukushima S, Nomachi A, Endo M, Wang Z, Inaba D, et al. Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerization. Mol Cell Biol. 2010;30:3610-9 pubmed publisher

product information

Catalog Number :

16-637

Subcategory :

Cell Signaling

Product Name :

Anti-Rac1 Antibody, clone 23A8, Agarose conjugate

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P63000

Host Name :

Mouse

Antigen :

Rac1

Isotype :

IgG2b

Product Description :

Anti-Rac1 Antibody, clone 23A8, Agarose conjugate

Cross Reactivity :

Human;Mouse;Rat

Background :

Rac is a member of the Rho family of small GTP-binding proteins, and plays roles in cytoskeletal actin organization as well as transformation. Rac is activated downstream of cdc42, or independently by Ras signaling, and in turn Rac stimulates Rho. Activation of Rac results in the formation of lamellipodia, whereas cdc42 stimulates filopodia formation, and Rho stimulates formation of actin stress fibers. Effectors of the Rac pathway include NADPH Oxidase and the SAPK1/JNK family of kinases. The latter pathway is activated by the PAK kinases, which are direct targets of Rac.

ALT Names :

Cell migration-inducing gene 5 protein;Ras-like protein TC25;migration-inducing gene 5;migration-inducing protein 5;ras-related C3 botulinum toxin substrate 1;ras-related C3 botulinum toxin substrate 1 (rho family,small GTP binding protein Rac1);ras-related C3 botulinum toxin substrate 1 isoform Rac1;rho family, small GTP binding protein Rac1

Immunogen :

Recombinant protein containing the full length human Rac1.

Specificity :

Recognizes Rac1 with a strong preference. There is a slight Rac2 cross-reactivity.

Package Size :

200 μL

Uses :

Immunoprecipitation

Storage :

Stable for 4 months at 2-8°C from date of receipt. DO NOT FREEZE! Wash the agarose beads with an appropriate buffer prior to use to remove sodium azide.