This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Phosphotyrosine Antibody, clone PY20, HRP Conjugate
catalog :
16-454
quantity :
10 blots
clonality :
monoclonal
host :
mouse
conjugate :
HRP
clone name :
PY20
application :
western blot, ELISA
citations: 33
Reference |
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von Bubnoff N, Gorantla S, Engh R, Oliveira T, Thöne S, Aberg E, et al. The low frequency of clinical resistance to PDGFR inhibitors in myeloid neoplasms with abnormalities of PDGFRA might be related to the limited repertoire of possible PDGFRA kinase domain mutations in vitro. Oncogene. 2011;30:933-43 pubmed publisher
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Zuckerman S, Kao W. LC/MS identification of 12 intracellular cytoskeletal and inflammatory proteins from monocytes adherent on surface-adsorbed fibronectin-derived peptides. J Biomed Mater Res A. 2008;85:513-29 pubmed
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Patel V, Rosenfeldt H, Lyons R, Servitja J, Bustelo X, Siroff M, et al. Persistent activation of Rac1 in squamous carcinomas of the head and neck: evidence for an EGFR/Vav2 signaling axis involved in cell invasion. Carcinogenesis. 2007;28:1145-52 pubmed
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product information
Catalog Number :
16-454
Subcategory :
Cell Signaling
Product Name :
Anti-Phosphotyrosine Antibody, clone PY20, HRP Conjugate
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
Varies
Host Name :
Mouse
Antigen :
Phosphotyrosine
Clone :
PY20
Conjugate :
HRP
Isotype :
IgG2b
Product Description :
Anti-Phosphotyrosine Antibody, clone PY20, HRP Conjugate
Cross Reactivity :
All
Background :
Protein tyrosine phosphorylation was first described in 1979. Large numbers of tyrosine kinases have been described since, and many of the signaling pathways initiated by tyrosine phosphorylation have been delineated. Availability of a top-quality anti-phosphotyrosine antibody has allowed the study of tyrosine kinase activity by simple blotting procedures, and without routine need of large quantities of radioactivity. The 4G10® monoclonal anti-phosphotyrosine antibody (Cat. # 05-321) has been widely recognized as a highly specific and sensitive. This antibody is suitable for all applications involving protein tyrosine phosphorylation. The slightly less sensitive, but still highly regarded clone PY20 can be used as an alternative to the 4G10® product line.
ALT Names :
PY20;anti-phosphotyrosine antibody
Immunogen :
Phosphotyrosine conjugated to carrier protein
Package Size :
10 blots
Uses :
Western Blotting;ELISA
Storage :
6 months at 2-8°C from date of shipment.
NOTE: DO NOT FREEZE. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany
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