Phosphotyrosine Antibody, clone 4G10®, Magnetic Bead Conjugate | EMD Millipore 16-282 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Phosphotyrosine Antibody, clone 4G10®, Magnetic Bead Conjugate

catalog :

16-282

quantity :

200 μL

clonality :

monoclonal

host :

mouse

conjugate :

Bead

antigen modification :

phosphorylated

clone name :

4G10®

application :

immunoprecipitation

product information

Catalog Number :

16-282

Subcategory :

Cell Signaling

Product Name :

Anti-Phosphotyrosine Antibody, clone 4G10®, Magnetic Bead Conjugate

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

Phosphotyrosine

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-Phosphotyrosine Antibody, clone 4G10®, Magnetic Bead Conjugate

Cross Reactivity :

All

Background :

Tyrosine phosphorylation is considered as one of the key steps in signal transduction and regulation of enzymatic activity. Some of the tyrosine residues can be tagged with a phosphate group (phosphorylated) by protein kinases. (In its phosphorylated state, it is referred to as phosphotyrosine.).The advent of anti-phosphotyrosine antibodies is one of significant events in signal transduction research. Before the availability of anti-phosphotyrosine antibodies, tyrosyl phospyhorylation of proteins and enzymes was investigated through hazardous and time-consuming radioactive experiments. Anti-phosphotyrosine antibodies are commonly used in western blots after the targeted proteins have been immunoprecipitated to measure the tyrosyl phosphorylation of the proteins. Anti-phosphotyrosine antibodies are also directly used on cell lysate to examine the overall change of tyrosine phosphorylation level in reponse to various treatments.

Immunogen :

Phosphotyramine-KLH

Specificity :

This antibody recognizes tyrosine-phosphorylated proteins from all species

Package Size :

200 μL

Uses :

Immunoprecipitation

Storage :

Stable for 1 year at 2-8ºC from date of receipt. Note: DO NOT FREEZE