Phospho-Histone H3 (Ser10) Antibody, clone 3H10, FITC Conjugate | EMD Millipore 16-222 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Phospho-Histone H3 (Ser10) Antibody, clone 3H10, FITC Conjugate

catalog :

16-222

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

3H10

reactivity :

human

application :

western blot, immunocytochemistry

citations: 5

Reference
Kogata N, Oliemuller E, Wansbury O, Howard B. Neuregulin-3 regulates epithelial progenitor cell positioning and specifies mammary phenotype. Stem Cells Dev. 2014;23:2758-70 pubmed publisher
Matthess Y, Raab M, Knecht R, Becker S, Strebhardt K. Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis. Mol Oncol. 2014;8:596-608 pubmed publisher
Zieba A, Pardali K, Söderberg O, Lindbom L, Nyström E, Moustakas A, et al. Intercellular variation in signaling through the TGF-? pathway and its relation to cell density and cell cycle phase. Mol Cell Proteomics. 2012;11:M111.013482 pubmed publisher
Ren K, Lu J, Porollo A, Du C. Tumor-suppressing function of caspase-2 requires catalytic site Cys-320 and site Ser-139 in mice. J Biol Chem. 2012;287:14792-802 pubmed publisher
Yoshida M, Feng L, Grimbert F, Rangarajan K, Buggele W, Copenhagen D, et al. Overexpression of neurotrophin-3 stimulates a second wave of dopaminergic amacrine cell genesis after birth in the mouse retina. J Neurosci. 2011;31:12663-73 pubmed publisher

product information

Catalog Number :

16-222

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Phospho-Histone H3 (Ser10) Antibody, clone 3H10, FITC Conjugate

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q16695

Host Name :

Mouse

Antigen :

Phospho-Histone H3 (Ser10)

Clone :

clone 3H10

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-Phospho-Histone H3 (Ser10) Antibody, clone 3H10, FITC Conjugate

Cross Reactivity :

Human

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

ALT Names :

H3S10P;Histone H3 (phospho S10);H3 histone family, member T;histone 3, H3;histone cluster 3, H3

Immunogen :

A proprietary immunogen based on a peptide sequence containing phospho-serine corresponding to residue 10 of human histone H3. Clone 3H10.

Specificity :

Recognizes histone H3 phosphorylated at Ser10, MW 17 kDa.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry;Immunofluorescence

Storage :

Stable for 1 year at from date of receipt.