ZAP-70 Antibody, clone 2F3.2, FITC conjugate | EMD Millipore 16-210 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

ZAP-70 Antibody, clone 2F3.2, FITC conjugate

catalog :

16-210

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

2F3.2

The same clone is also sold as:

LifeSpan Biosciences: LS-C348627, LS-C202918, LS-C87914, LS-C312206
OriGene: TA327755, AM10148SU-N
Invitrogen: MA5-12624
Dako: M7303
MyBioSource: MBS370118
Abnova: MAB13456, MAB13455
Novus Biologicals: NBP2-44502-0.1mg, NBP2-47774-0.1mg

reactivity :

human

application :

western blot, immunocytochemistry, flow cytometry

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Negrini M, Cutrona G, Bassi C, Fabris S, Zagatti B, Colombo M, et al. microRNAome expression in chronic lymphocytic leukemia: comparison with normal B-cell subsets and correlations with prognostic and clinical parameters. Clin Cancer Res. 2014;20:4141-53 pubmed publisher
flow cytometry; human	Gentile M, Cutrona G, Mosca L, Matis S, Fabris S, Lionetti M, et al. Prospective validation of a risk score based on biological markers for predicting progression free survival in Binet stage A chronic lymphocytic leukemia patients: results of the multicenter O-CLL1-GISL study. Am J Hematol. 2014;89:743-50 pubmed publisher
flow cytometry; human	Morabito F, Mosca L, Cutrona G, Agnelli L, Tuana G, Ferracin M, et al. Clinical monoclonal B lymphocytosis versus Rai 0 chronic lymphocytic leukemia: A comparison of cellular, cytogenetic, molecular, and clinical features. Clin Cancer Res. 2013;19:5890-900 pubmed publisher
flow cytometry; human	Gentile M, Cutrona G, Fabris S, Pesce E, Baldini L, Di Raimondo F, et al. Total body computed tomography scan in the initial work-up of Binet stage A chronic lymphocytic leukemia patients: Results of the prospective, multicenter O-CLL1-GISL study. Am J Hematol. 2013;88:539-44 pubmed publisher
	Szánthó E, Bhattoa H, Csobán M, Antal Szalmas P, Ujfalusi A, Kappelmayer J, et al. Serum thymidine kinase activity: analytical performance, age-related reference ranges and validation in chronic lymphocytic leukemia. PLoS ONE. 2014;9:e91647 pubmed publisher
	Rossi M, Fuligni F, Ciccone M, Agostinelli C, Righi S, Luciani M, et al. Hsa-miR-15a and Hsa-miR-16-1 expression is not related to proliferation centers abundance and other prognostic factors in chronic lymphocytic leukemia. Biomed Res Int. 2013;2013:715391 pubmed publisher
	Best O, Che Y, Singh N, Forsyth C, Christopherson R, Mulligan S. The Hsp90 inhibitor SNX-7081 synergizes with and restores sensitivity to fludarabine in chronic lymphocytic leukemia cells with lesions in the TP53 pathway: a potential treatment strategy for fludarabine refractory disease. Leuk Lymphoma. 2012;53:1367-75 pubmed publisher
	Sulda M, Kuss B, Hall R, Bailey S, Macardle P. Clinical utility of molecular and flow cytometric markers in chronic lymphocytic leukaemia. Intern Med J. 2012;42:137-46 pubmed publisher
	Grever M, Lucas D, Dewald G, Neuberg D, Reed J, Kitada S, et al. Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997. J Clin Oncol. 2007;25:799-804 pubmed

product information

Catalog Number :

16-210

Subcategory :

Cell Signaling

Product Name :

Anti-ZAP-70 Antibody, clone 2F3.2, FITC conjugate

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P43403

Host Name :

Mouse

Antigen :

ZAP-70

Clone :

clone 2F3.2

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-ZAP-70 Antibody, clone 2F3.2, FITC conjugate

Cross Reactivity :

Human;Rat

Background :

ZAP70, a 70 kDa member of the Syk tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Mutations in ZAP70 gene results in a form of Severe Combined Immunodeficiency Syndrome (SCID) in humans. ZAP70 expression also defines a subset of Chronic Lymphocytic Leukemia (CLL) in patients with unmutated Ig gene and poor clinical course.

ALT Names :

70 kDa zeta-associated protein;Syk-related tyrosine kinase;zeta-chain (TCR) associated protein kinase (70 kD);zeta-chain (TCR) associated protein kinase 70kDa;zeta-chain associated protein kinase 70kDa;zeta-chain associated protein kinase, 70kD

Immunogen :

GST-fusion protein containing the 2 tandem SH2 domains of human ZAP-70 correspon-ding to amino acids 1-254. Clone 2F3.2.

Specificity :

Recognizes human ZAP-70.

Package Size :

100 µg

Uses :

Flow Cytometry;Immunocytochemistry;Western Blotting

Storage :

Stable for 6 months at 2-8°C from date of receipt. For maximum recovery of product, centrifuge original vial prior to removing cap.