Histone H3.3 Antibody | EMD Millipore 09-838 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Histone H3.3 Antibody

catalog :

09-838

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, chicken

application :

western blot, immunocytochemistry, chromatin immunoprecipitation, ChIP-Seq

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1a	Gomes A, Ilter D, Low V, Rosenzweig A, Shen Z, Schild T, et al. Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization. Cancer Cell. 2019;36:402-417.e13 pubmed publisher
western blot; human; loading ...; fig 2a	Zhang X, Li B, Rezaeian A, Xu X, Chou P, Jin G, et al. H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis. Nat Commun. 2017;8:14799 pubmed publisher
western blot; human; loading ...; fig 5c	Yang J, Song T, Jo C, Park J, Lee H, Song I, et al. Differential regulation of the histone chaperone HIRA during muscle cell differentiation by a phosphorylation switch. Exp Mol Med. 2016;48:e252 pubmed publisher
western blot; mouse; fig 1s1	Deaton A, Gómez Rodríguez M, Mieczkowski J, Tolstorukov M, Kundu S, Sadreyev R, et al. Enhancer regions show high histone H3.3 turnover that changes during differentiation. elife. 2016;5: pubmed publisher
ChIP-Seq; chicken; fig 3	Romanello M, Schiavone D, Frey A, Sale J. Histone H3.3 promotes IgV gene diversification by enhancing formation of AID-accessible single-stranded DNA. EMBO J. 2016;35:1452-64 pubmed publisher
western blot; human; fig 1	Jayaram H, Hoelper D, Jain S, Cantone N, Lundgren S, Poy F, et al. S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3. Proc Natl Acad Sci U S A. 2016;113:6182-7 pubmed publisher
	Nagaraja S, Quezada M, Gillespie S, Arzt M, Lennon J, Woo P, et al. Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State. Mol Cell. 2019;76:965-980.e12 pubmed publisher
	Xiong C, Wen Z, Yu J, Chen J, Liu C, Zhang X, et al. UBN1/2 of HIRA complex is responsible for recognition and deposition of H3.3 at cis-regulatory elements of genes in mouse ES cells. BMC Biol. 2018;16:110 pubmed publisher
	Voon H, Udugama M, Lin W, Hii L, Law R, Steer D, et al. Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma. Nat Commun. 2018;9:3142 pubmed publisher

product information

Catalog Number :

09-838

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Histone H3.3 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P84243

Host Name :

Rabbit

Antigen :

Histone H3.3

Conjugate :

Affinity Purified

Product Description :

Anti-Histone H3.3 Antibody

Cross Reactivity :

Human;Mouse

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. Histone variant H3.3 is typically enriched in active chromatin.

ALT Names :

Histone H3.3

Immunogen :

KLH-conjugated linear peptide corresponding to human Histone H3.3.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry;Dot Blot;Chromatin Immunoprecipitation (ChIP)

Storage :

Stable for 1 year at 2-8°C from date of receipt