KLF4 Antibody | EMD Millipore 09-821 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

KLF4 Antibody

catalog :

09-821

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry

citations: 1

Reference
Katayama M, Hirayama T, Kiyono T, Onuma M, Tani T, Takeda S, et al. Immortalized prairie vole-derived fibroblasts (VMF-K4DTs) can be transformed into pluripotent stem cells and provide a useful tool with which to determine optimal reprogramming conditions. J Reprod Dev. 2017;63:311-318 pubmed publisher

product information

Catalog Number :

09-821

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-KLF4 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q60793

Host Name :

Rabbit

Antigen :

KLF4

Conjugate :

Affinity Purified

Product Description :

Anti-KLF4 Antibody

Cross Reactivity :

Mouse;Human

Background :

Krüppel-like factors (KLFs) are zinc finger-containing transcription factors with regulatory functions in cell growth, proliferation, differentiation, and embryogenesis. Krüppel-like factor 4 (Klf4) has diverse functionss and acts as both an activator and repressor of transcription. The Klf protein has been shown to activate its own transcription throught its interaction with CACCC core sequences. High expression of Klf4 is observed in differentiating layers of epidermis and a loss of expression results in a break-down of barrier function including protection against pathogen invasion and dehydration. KLF4 is also associated with other biological functions such as proliferation, differentiation and carcinogenesis in gastrointestinal tissues. After DNA damage, Klf4 has been shown to induce DNA repair pathways. Klf4 seems to hinder prostate cancer tumor cell growth and migration.

ALT Names :

Kruppel-like factor 4 (gut);Gut-enriched krueppel-like factor;endothelial Kruppel-like zinc finger protein;Krueppel-like factor 4;Epithelial zinc finger protein EZF;Krüppel-like factor;klf

Immunogen :

GST-tagged recombinant protein corresponding to the N-terminus of mouse Klf4.

Specificity :

This antibody recognizes Klf4 at the N-terminus.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt