CARM1 Antibody | EMD Millipore 09-818 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CARM1 Antibody

catalog :

09-818

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, western blot knockout validation

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; 1:1000; loading ...; fig 1c	Quintero C, Laursen K, Mongan N, Luo M, Gudas L. CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation. J Mol Biol. 2018;430:4168-4182 pubmed publisher
	Greenblatt S, Man N, Hamard P, Asai T, Karl D, Martínez C, et al. CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis. Cancer Cell. 2018;33:1111-1127.e5 pubmed publisher

product information

Catalog Number :

09-818

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-CARM1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q9WVG6

Host Name :

Rabbit

Antigen :

CARM1

Conjugate :

Purified

Product Description :

Anti-CARM1 Antibody

Cross Reactivity :

Human;Rat

Background :

CARM1 (coactivator-associated arginine methyltransferase 1) is an arginine N-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to arginine residues within proteins. CARM1 targets include methylation of histone H3 at Arg17 and p300 at Arg2142. CARM1 is recruited to promoters upon gene activation together with histone acetyltransferases from the p300 and p160 families. During monocyte inflammatory stimulation, CARM1 acts together with p300 as a coactivator for NF-kB. It is responsible for moving cells toward the inner cell mass in developing blastocysts. CARM1 also plays an important role in androgen receptors and may play a role in prostate cancer progression.

ALT Names :

Protein arginine N-methyltransferase 4;coactivator-associated arginine methyltransferase 1 ;coactivator-associated arginine methyltransferase-1

Immunogen :

KLH-conjugated, synthetic peptide containing the sequence (CSPMSIPTNTMHYGS), corresponding to a.a. 595-608 of human CARM1.

Specificity :

Recognizes CARM1, Mr ~60 kDa.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt. For maximum recovery of product, centrifuge the vial prior to removing the cap.