JMJD2A Antibody | EMD Millipore 09-809 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

JMJD2A Antibody

catalog :

09-809

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, chimpanzee

application :

western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation

product information

Catalog Number :

09-809

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-JMJD2A Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

O75164

Host Name :

Rabbit

Antigen :

JMJD2A

Conjugate :

Affinity Purified

Product Description :

Anti-JMJD2A Antibody

Cross Reactivity :

Human;Mouse;Chimpanzee;Rhesus Macaque

Background :

Jumonji domain-containing protein 2A (JMJD2A) is a nuclear and cytoplasmic member of the JMJD2 family, a group of proteins characterized as containing a JmjC domain, a JmjN domain, two PHD-type zinc finger domains, and 2 Tudor domains. Little is known about the function for most of these domains; however, they are believed to be involved in transcriptional regulation. JMJD2A functions as a histone demethylase with specific activity against trimethylated Histone H3 Lysine residues Lys-9 and Lys-36. It has no effect on any other lysine residues, or on mono- and dimethylated Lys-9 and Lys-36. The demethylation of these residues induces the production of succinate and formaldehyde. Studies have shown JMJD2A to recruit NCOR1 and histone deacetylases, causing the respective transcriptional repression of E2F- and ASCL2 responsive promoters. JMJD2A is ubiquitously expressed in human cell lines and tissues.

ALT Names :

JMJD;lysine (K)-specific demethylase 4A;JmjC domain-containing histone demethylation protein 3A;jumonji domain containing 2A;jumonji C domain-containing histone demethylase 3A;jumonji domain containing 2;lysine-specific demethylase 4A;Jumonji domain-containing protein 2A

Immunogen :

KLH-conjugated linear peptide corresponding to human JMJD2A.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry;Chromatin Immunoprecipitation (ChIP)

Storage :

Stable for 1 year at 2-8°C from date of receipt