phospho-Histone H3(Ser10) Antibody | EMD Millipore 09-797 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho-Histone H3(Ser10) Antibody

catalog :

09-797

quantity :

400 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

citations: 1

Reference
Poulton J, Cuningham J, Peifer M. Centrosome and spindle assembly checkpoint loss leads to neural apoptosis and reduced brain size. J Cell Biol. 2017;216:1255-1265 pubmed publisher

product information

Catalog Number :

09-797

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-phospho-Histone H3(Ser10) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P84243

Host Name :

Rabbit

Antigen :

phospho-Histone H3(Ser10)

Conjugate :

Purified

Product Description :

Anti-phospho-Histone H3(Ser10) Antibody

Cross Reactivity :

Human

Background :

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

ALT Names :

H3S10P;Histone H3 (phospho S10);H3 histone, family 3A

Immunogen :

The immunogen was MAPS conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Ser10 of human histone cluster 1, H3B.

Specificity :

This antibody recognizes histone H3 phosphorylated at Ser10.

Package Size :

400 µL

Uses :

Western Blotting;ELISA;Immunohistochemistry

Storage :

Stable for 6 months at 2-8°C from date of receipt. For long term storage, store at -20ºC. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.