c-Jun Antibody | EMD Millipore 09-754 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

c-Jun Antibody

catalog :

09-754

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dogs, chicken, bovine

application :

western blot

product information

Catalog Number :

09-754

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-c-Jun Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P45983

Host Name :

Rabbit

Antigen :

c-Jun

Conjugate :

Purified

Product Description :

Anti-c-Jun Antibody

Cross Reactivity :

Human;Mouse;Rat;Bovine;Chicken;Canine

Background :

c-Jun is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun.

ALT Names :

JNK1 alpha protein kinase ;JNK1 beta protein kinase ;JUN N-terminal kinase ;Stress-activated protein kinase JNK1 ;c-Jun N-terminal kinase 1;mitogen-activated protein kinase 8;mitogen-activated protein kinase 8 isoform JNK1 alpha1 ;mitogen-activated protein kinase 8 isoform JNK1 beta2 ;protein kinase JNK1

Immunogen :

KLH-conjugated linear peptide corresponding to the internal domain of c-Jun.

Specificity :

This antibody recognizes the internal domain of c-Jun.

Package Size :

100 µg

Uses :

Western Blotting

Storage :

Stable at 2-8°C for 1 year from date of recipt.