RING1 Antibody | EMD Millipore 09-706 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

RING1 Antibody

catalog :

09-706

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dog, cow

application :

western blot

product information

Catalog Number :

09-706

Subcategory :

Cell Signaling

Product Name :

Anti-RING1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q06587

Host Name :

Rabbit

Antigen :

RING1

Conjugate :

Affinity Purified

Product Description :

Anti-RING1 Antibody

Cross Reactivity :

Human;Mouse;Horse;Bovine;Pig;Canine;Mouse

Background :

RING1 belongs to the RING finger family, members of which are characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. RING is one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.

ALT Names :

Polycomb complex protein RING1;ring finger protein 1

Immunogen :

KLH-conjugated linear peptide corresponding to human RING1.

Specificity :

This antibody recognizes RING1.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt